REACTIVE BLUE FC 75311

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:

solubility in organic solvents / fat solubility

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

February 01 to February 11 2000

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted to recognised test guideline in compliance with GLP.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2000

Report date:

2000

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)

Deviations:

no

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

419-480-1

EC Name:

-

IUPAC Name:

Reaction mass of tetrasodium 2-((1-(3-(6-fluoro-(4-((N-(2-(2-sulfatoethanesulfonyl)ethyl)-N-phenyl)amino)-1,3,5-triazin-2-ylamino)-2-hydroxy-5-sulfonatophenylazo)-1-phenylmethyl)azo)-4-sulfonatobenzoate cuprate (4-) and trisodium 2-((1-(3-((4-(N-(2-ethenesulfonylethyl)-N-phenyl)amino)-6-fluoro-1,3,5-triazin-2-ylamino)-2-hydroxy-5-sulfonatophenylazo)-1-phenylmethyl)azo)-4-sulfonatobenzoate cuprate (4-)

Details on test material:

- Name of test material (as cited in study report): Reaktiv Blau FC 75311

Results and discussion

Solubility in organic solvents / fat solubility

Medium:

standard fat

Remarks:

HB307

Solubility:

< 0.003 mg/100 g solvent

Temp.:

20 °C

Remarks on result:

other: Measurements taken in 100 g fat at 37 °C

Test substance stable:

yes

Details on results:

See below

Any other information on results incl. tables

Details of the experiments:

 

Experiment	Pre-saturation		Stirring time at 37 °C (h)	Mass ratio Dissolved test substance/fat (mg/100 g)
No.	Stirring time (h)	Temperature (°C)
1	3.0	30	3	< 0.003
2	3.0	30	3	< 0.003
3	3.0	30	27	< 0.003
4	3.0	30	27	< 0.003
5	3.0	50	3	< 0.003
6	3.0	50	3	< 0.003
7	3.0	50	27	0.003
8	3.0	50	27	< 0.003

 

 Thus the ratio test substance per 100 g fat was calculated from the concentration of the lowest calibration standard (detection limit).

 

For evaluation of the result one has to take into account that the spectrometric measurements only include organic components showing absorption at the quantification wavelength.

Applicant's summary and conclusion

Conclusions:

The substance has been shown to be virtually insoluble in fat.

Executive summary:

The substance has been shown to be virtually insoluble in fat. This, coupled with the low partition coefficient value indicates that the substance is unlikely to be prone to bioaccumulation in its registered form.