Registration Dossier
Registration Dossier
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EC number: 270-126-0 | CAS number: 68411-44-9
Carcinogenicity
Administrative data
- Endpoint:
- carcinogenicity
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Regulatory accepted model for assessment of chemical substances
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR modeling
- Principles of method if other than guideline:
- CAESAR QSAR model for Carcinogenicity - version 1.0.0.6
- GLP compliance:
- no
- Remarks:
- not applicable to QSAR models
Test material
- Reference substance name:
- Butylbenzene
- EC Number:
- 203-209-7
- EC Name:
- Butylbenzene
- Cas Number:
- 104-51-8
- Molecular formula:
- C10H14
- IUPAC Name:
- butylbenzene
- Reference substance name:
- sec-butylbenzene
- EC Number:
- 205-227-0
- EC Name:
- sec-butylbenzene
- Cas Number:
- 135-98-8
- Molecular formula:
- C10H14
- IUPAC Name:
- sec-butylbenzene
- Reference substance name:
- tert-butylbenzene
- EC Number:
- 202-632-4
- EC Name:
- tert-butylbenzene
- Cas Number:
- 98-06-6
- Molecular formula:
- C10H14
- IUPAC Name:
- tert-butylbenzene
- Reference substance name:
- Isobutylbenzene
- EC Number:
- 208-706-2
- EC Name:
- Isobutylbenzene
- Cas Number:
- 538-93-2
- IUPAC Name:
- isobutylbenzene
- Reference substance name:
- p-cymene
- EC Number:
- 202-796-7
- EC Name:
- p-cymene
- Cas Number:
- 99-87-6
- Molecular formula:
- C10H14
- IUPAC Name:
- 1-isopropyl-4-methylbenzene
- Reference substance name:
- m-cymene
- EC Number:
- 208-617-9
- EC Name:
- m-cymene
- Cas Number:
- 535-77-3
- Molecular formula:
- C10H14
- IUPAC Name:
- 1-isopropyl-3-methylbenzene
- Details on test material:
- Component substances
Constituent 1
Constituent 2
Constituent 3
Constituent 4
Constituent 5
Constituent 6
Results and discussion
Any other information on results incl. tables
Activity: Non-Positive (refer CSR)
Applicant's summary and conclusion
- Conclusions:
- Screening assessment of butylbenzene components with the available QSAR models does not identify them as substances with mutagenic/genotoxicand carcinogenic properties.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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