Registration Dossier
Registration Dossier
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EC number: 224-207-2 | CAS number: 4246-51-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to fish.
Key value for chemical safety assessment
Additional information
The acute fish toxicity of 3,3'-oxybis(ethyleneoxy)bis(propylamine) (CAS 4246 -51 -9) was determined with Leuciscus idus according to the German Industrial Standard DIN 38412, L15. The test item concentrations were not analytically verified. However, it is assumed that the test concentrations remained stable over the exposure period based on a high water solubility, a low potential to evaporate into air (Henry’s Law constant < 1 Pa*mol/cm³) and a low potential for adsorption (log Kow and log Koc < 3). The test solutions were not pH-adjusted except for the highest test concentration (1000 mg/L) which was tested in parallel after pH-adjustment. The test substance causes a pH-shift to more alkaline conditions with increasing concentrations, resulting in a maximum pH value of 11 in the highest test concentration (1000 mg/L). The acceptable pH range for fish given in the OECD TG 203 (pH 6.0 to 8.5) was therefore not kept in all test concentrations.
The obtained LC50(96 h) was > 215 - < 464 mg/L under non-neutralised test conditions. After pH-adjustment no mortality was observed at 1000 mg/L. Hence, the observed effects were caused by the alkaline pH shift in the test medium (BASF AG, 1991; report no. 10F0229/875168). Based on the available data, the test substance is with high probability acutely not harmful to fish.
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