Registration Dossier
Registration Dossier
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EC number: 606-946-6 | CAS number: 221640-14-8
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- yes
- Remarks:
- no duplicate measurements.
- Principles of method if other than guideline:
- No determination by testing the sample at least in duplicate
- GLP compliance:
- no
- Type of method:
- other: Differential scanning calorimetry (DSC)
- Melting / freezing pt.:
- 220 °C
- Remarks on result:
- other: No pressure is reported
- Conclusions:
- Carbamic acid [(1S)-,2-[(2-aminoethyl)amino]-1-[(4-ethoxyphenyl)methyl]ethyl]-,phenylmethyl ester, dihydrochloride (9Cl) melts at 220 °C and no pressure was reported.
- Executive summary:
The melting point of carbamic acid [(1S)-,2-[(2-aminoethyl)amino]-1-[(4-ethoxyphenyl)methyl]ethyl]-,phenylmethyl ester, dihydrochloride (9Cl) of 220 °C was tested according to OECD Guideline 102 by DSC measurements with a heating rate of 10 K/min on a NETZSCH-DSC 204 F1 Phoenix ASC in aluminum crucibles with perforated lids and no pressure was reported.
Reference
The result showed that a sharp and endothermic signal of -162 J/g occurs between 199 and 252 °C with a peak maximum at 223 °C.
Description of key information
Carbamic acid [(1S)-,2-[(2-aminoethyl)amino]-1-[(4-ethoxyphenyl)methyl]ethyl]-,phenylmethyl ester, dihydrochloride (9Cl) melts at 220 °C and no pressure was reported.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 220 °C
Additional information
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