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Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
13 Nov 1987 to 17 Nov 1987
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes
Type of method:
flask method
Water solubility:
100 mg/L
Conc. based on:
test mat.
Loading of aqueous phase:
556.8 mg/L
Incubation duration:
>= 1 - <= 3 d
Temp.:
30 °C
pH:
6.9
Remarks on result:
other: St. Dev.: 0.0082 g/L
Details on results:
See 'Any other information on results incl. tables' for an overview ofthe results

Sample No.

1

2

3

mg material weighed in

14.54

14.04

13.18

mL of water

25

25

25

Date/ time

 

 

 

Start of expt. 30°

15.11/08.30

14.11/09.20

13.11/08.30

Removed from 30°

16.11/09.00

16.11/09.00

16.11/09.00

Analysed at 20°

17.11/10.10

17.11/10.15

17.11/10.20

pH after equilibration

6.9

6.9

6.9

Concentration found g/L

0.098

0.109

0.093

Average Solubility g/L

0.100

 

Conclusions:
The water solubility of the test item was determined to be 100 mg/L in water at 20 °C and pH = 6.9.
Executive summary:

This study was performed in accordance with the OECD TG 105 (1981) and the EC method A.6. (1992) and in compliance with GLP. The solubility of the pure active ingredient in water was determined to be 100 mg/L at 20 °C and pH = 6.9.

Description of key information

110 mg/L at 25 °C, OECD TG 105, flask method, Vijayakumar 2011

Key value for chemical safety assessment

Water solubility:
110 mg/L
at the temperature of:
25 °C

Additional information