Registration Dossier
Registration Dossier
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EC number: 203-764-5 | CAS number: 110-40-7
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- GLP compliance:
- not specified
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Key result
- Type:
- log Pow
- Partition coefficient:
- 4.64
- Temp.:
- 20 °C
- pH:
- 7.1
- Conclusions:
- The partition coefficient at 20 °C of the test item Diethyl Sebacate was determined by means of the HPLC method, according to regulation EC No. 440/2008 method A.8., Regulation EC No. 2016/266 method A.24., and OECD Test Guideline 117 (2004) to be : log Pow = 4.64 ± < 0.0
- Executive summary:
For that endpoint, one reliable study performed on the registered substance and according to the OECD 117 guideline was available.
Under the experimental conditions, the partition coefficient of the sample " Diethyl sebacate" is 4.64 at 20°C. This value was determined by means of the HPLC method.
The validity criteria were successful and the study was therefore regarded as acceptable for that endpoint.
Reference
Description of key information
For that endpoint, one reliable study performed on the registered substance and according to the OECD 117 guideline was available.
Under the experimental conditions, the partition coefficient of the sample " Diethyl sebacate" is 4.64 at 20°C. This value was determined by means of the HPLC method.
The validity criteria were successful and the study was therefore regarded as acceptable for that endpoint.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.64
- at the temperature of:
- 20 °C
Additional information
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