Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Test material form:
- liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Remarks:
- ICP/OES
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- Freshwater unicellular green alga Pseudokirchneriella subcapitata of the chlorococcal order strain number CCAP 278.4 was used in this study.
Study design
- Test type:
- not specified
- Water media type:
- other: ultrapure water
- Limit test:
- no
- Total exposure duration:
- 72 h
Test conditions
- Hardness:
- not specified
- Test temperature:
- 22.7 °C – 23.3°C
- pH:
- 7.5 (t=0) to 9.4 (t=72h)
- Dissolved oxygen:
- not specified
- Nominal and measured concentrations:
- 10, 32, 102, 328, 1050 mg/L
- Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EL50
- Effect conc.:
- ca. 139.9 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EL50
- Effect conc.:
- ca. 141.7 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: yield inhibition
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The results obtained for the test item “ W3803S04SOLSIV” on the toxicological endpoint “inhibition of growth rate” indicate an ErL50-(0-72h) = 139.9 mg/L [99.4 – 200.3], based on nominal test item loading rate.
The results obtained for the test item “ W3803S04SOLSIV” on the toxicological endpoint “Yield inhibition” indicate an EyL50-(0-72h) = 141.7 mg/L [93.6 – 222.7], based on nominal test item loading rate.
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