Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 433-470-4 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Acute toxicity study in the earthworm Eisenia fetida fetida with SETAFIX Z1077.
The study procedures described in this report were based on OECD guideline for Testing of Chemicals No. 207 (adopted April 4, 1984). In addition, the procedure was designed to meet the test methods prescribed by Council regulation (EC) No 440/2008 of 30 May 2008, Part C: Methods for the determination of ecotoxicity, Publication No. L142, C.8. "Toxicity for earthworms".
A limit test was performed exposing forty earthworms (10 per replicate, 4 replicates) to an untreated control and 1000 mg SETAFIX Z1077/kg d.s. In addition, ten earthworms (1 replicate) per group were exposed to 1.0, 10 and 100 mg/kg d.s. in a range-finding test. Test duration was 14 days.
SETAFIX Z1077 did not cause mortality of Eisenia fetida fetida at 1000 mg/kg d.s. after 14 days of exposure (NOEC).
The 14-day LC50was beyond the range tested; i.e. exceeded a concentration of 1000 mg/kg d.s.
The 14-day EC50for body weight reduction was beyond the range tested; i.e. exceeded a concentration of 1000 mg/kg d.s.
As part of the information requirements as laid down in Section 9.4.2 Annex IX of the REACH Regulation the registrant proposes to investigate effects on soil microorganisms of the test substance, 1,6-Bis(methoxybenzoyloxy)hexane, with respect to the nitrogen transformation by soil microorganisms (EU Method C.21., Nitrogen transformation test). Moreover, a potential effect on the transformation of nitrogen by soil micro-organisms was indicated as a concern in the EU-Risk Assessment Report in 2001 and the test proposed addresses this concern.
As the information on this endpoint is not available for the registered substance but is needed in the technical dossier to meet the information requirements and, thus necessary to generate the data and to perform the test.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
