Registration Dossier
Registration Dossier
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EC number: 201-431-9 | CAS number: 82-58-6
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
Ames:
One study in 2018 shows positive to tester strains TA1537, TA98, TA100 and WP2uvrA in the absence of S9-mix, and the results were reproducible in a follow up experiment, these increases are considered to be biologically relevant and the test item is considered to be mutagenic.
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (positive)
Additional information
Justification for classification or non-classification
Positive result in Ames study.
Therefore in accordance with Regulation (EC) No. 1272/2008 Table 3.5.1, this substance should be classified as a Category 2 mutagen.
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