Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation / corrosion, other
Type of information:
other: Extimation by a decision tree
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Results are derived from a valid Toxtree application, but with limited documentation/justification

Data source

Reference
Reference Type:
other: TOXTREE
Title:
Skin irritation/corrosion

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.

Test material

Details on test material:
The SMILES included in the reference substance linked in Section 1 (General information) was used as model input.

Results and discussion

Any other information on results incl. tables

The substance is extimated as not corrosive to skin.

The following input data were reported:

- Melting point= 124 °C

- Lipid solubility= silent, since no data ias available

- Water solubility= 0.01231 g/L

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
The substance is considered not to be corrosive for skin, however the model is not able to exclude the skin irritation.
The study cannot be used for classification.