Registration Dossier
Registration Dossier
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EC number: 221-493-0 | CAS number: 3119-15-1
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- other: Structural analysis
- Adequacy of study:
- other information
- Study period:
- 10 Oct 2000
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 000
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Information on hydrolytic stability of ZK 2218 was to be obtained as a contribution to the Schering project ìEcotoxicological Evaluation of Starting Materials, Intermediates and Drug Substancesî. The project is part of the ìFreiwillige Selbstverpflichtung der deutschen chemischen Industrie f¸r die Erfassung und Bewertung von Stoffenî (voluntary self commitment of the German chemical industry to catalogue and evaluate chemicals) as promoted by the VCI
(Verband der Chemischen Industrie).
The guidance provided by the VCI (Ref. 1) calls for valid data with respect to the aim of the project, namely to gain information on the behavior or the persistence and fate of such compounds in the environment. Within the scope of the project conclusions are acceptable as drawn on basis of analogies to similar compounds or as derived from knowledge regarding the behavior of chemical structures and functional groups (Ref. 2).
Test material
- Reference substance name:
- 3-amino-2,4,6-triiodobenzoic acid
- EC Number:
- 221-493-0
- EC Name:
- 3-amino-2,4,6-triiodobenzoic acid
- Cas Number:
- 3119-15-1
- Molecular formula:
- C7H4I3NO2
- IUPAC Name:
- 3-amino-2,4,6-triiodobenzoic acid
- Test material form:
- solid: bulk
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- ZK 2218 does not contain functional groups which are susceptible to hydrolytic cleavage.
ZK 2218 is to be considered hydrolytically stable in the relevant pH region 4 - 9. - Executive summary:
ZK 2218 does not contain functional groups which are susceptible to hydrolytic cleavage. ZK 2218 is to be considered hydrolytically stable in the relevant pH region 4 - 9.
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