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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

Currently viewing:

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: peer-reviewed database

Data source

Reference
Reference Type:
secondary source
Title:
Cobalt, di-mu-carbonylhexacarbonyldi-, (Co-Co)
Author:
RTECS
Year:
2017
Bibliographic source:
http://ccinfoweb.ccohs.ca/rtecs/search.html [VRDEA5 Vrachebnoe Delo. Medical Practice. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1918- Volume (issue)/page/year: (2),101,1969]

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
not specified in database
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Octacarbonyldicobalt
EC Number:
233-514-0
EC Name:
Octacarbonyldicobalt
Cas Number:
10210-68-1
Molecular formula:
C8O8Co2
IUPAC Name:
1,1,1,3,3,3-hexakis(oxidaniumylidynemethyl)-2,4-dioxo-1,3-dicobaltabicyclo[1.1.0]butane-1,1,3,3-tetrakis(ylium)

Test animals

Species:
rat

Administration / exposure

Route of administration:
inhalation

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LC50
Effect level:
165 mg/m³ air
Based on:
test mat.
Remarks on result:
other: toxic effects: Lungs, Thorax, or Respiration - acute pulmonary edema

Applicant's summary and conclusion

Conclusions:
LC50 (inhalation, rat) = 165 mg/m^3
Executive summary:

There is no available information on the methods used to determine the value for this endpoint. However, this information is taken from RTECS database which is considered to be a reliable peer reviewed database. The LC50 (inhalation, rat) of the substance has been reported to be 165 mg/m3.