Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 206-017-1 | CAS number: 288-13-1
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- GLP compliance:
- no
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- 0.33
- Temp.:
- 25 °C
- pH:
- 7
- Conclusions:
- The log Kow of the test substance is 0.33 at 25°C at pH 7.0.
- Executive summary:
The partition coefficient of the test substance was measured in accordance with OECD Guideline 117. The partition coefficient of the test substance is 0.33 at 25°C at pH 7.0.
Reference
In order to determine the log Pow of the test substance, the measured Log k 'values of the test substances were applied against the log Pow values.
The regression lines obtained thereby have the function:
1) Eluent water / methanol:
log Pow 1,446 * log k'+ 0,218
From this a log Pow of the test substance of 0,23 results.
2) Eluent buffer / methanol:
log Pow 1,427 * log k'+ 0,241
From this a log Pow of the test substance of 0,33 results.
The partition coefficient log Pow of the test substance is 0.23 (measured against water/methanol) or 0,33 (measured against buffer pH7/Methanol).
Description of key information
OECD Guideline 117
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 0.33
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
