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EC number: 201-140-7
CAS number: 78-76-2
Dose range finding test/Mutation experiment 1
Toxicity: In strain TA1537 (absence of S9-mix), a fluctuation in the
number of revertant colonies below the laboratory historical control
data range was observed at the mid dose level of 512 μg/plate. However,
since no dose-relationship was observed, this reduction is not
considered to be caused by toxicity of the test item. This reduction is
more likely caused by an incidental fluctuation in the number of
Mutation experiment 2
Mutagenicity: In tester strain TA1535, an increase above the historical
control data range was observed at the highest tested dose level in the
presence of S9-mix. However, since this increase was just above the
historical control data range, only observed in the second mutation
experiment, and was not dose-related and not three-fold (a maximum of
2.1-fold was reached), this increase was considered to be not
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