Ethyl undec-10-enoate

Toxicity to soil macroorganisms except arthropods

Administrative data

Endpoint:

toxicity to soil macroorganisms except arthropods: short-term

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Guideline study with acceptable restrictions

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1999

Report date:

1999

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 207 (Earthworm, Acute Toxicity Tests)

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

Isopropyl myristate

EC Number:

203-751-4

EC Name:

Isopropyl myristate

Cas Number:

110-27-0

Molecular formula:

C17H34O2

IUPAC Name:

isopropyl myristate

Sampling and analysis

Analytical monitoring:

no

Test substrate

Vehicle:

no

Test organisms

Test organisms (species):

Eisenia fetida

Animal group:

annelids

Details on test organisms:

TEST ORGANISM
- Common name: redworms
- Source: in-house breed, originally obtained from Regenwurmfarm Tacke
- Age at test initiation: 3 - 6 months
- Mean Weight: 361.3 ± 65.7 mg

Study design

Study type:

laboratory study

Substrate type:

artificial soil

Limit test:

yes

Total exposure duration:

14 d

Test conditions

Test temperature:

20 ± 2 °C

pH:

Begin: 6.42
End: 6.50

Moisture:

26.1 - 26.5%

Details on test conditions:

TEST SYSTEM
- Test container: 1000 mL glass beaker covered with a perforated foil
- Amount of soil or substrate: 750 g substrate
- No. of organisms per container (treatment): 10
- No. of replicates per treatment group: 4
- No. of replicates per control: 4

SOURCE AND PROPERTIES OF SUBSTRATE (if soil)
- Composition (if artificial substrate): 10% sphagnum peat, 20% kaolin, 70% quartzsand, CaCO3 to adjust pH

OTHER TEST CONDITIONS
- Photoperiod: 24 hours permanent, diffuse light
- Light intensity: 500 Lux

EFFECT PARAMETERS MEASURED: mortality after 7 and 14 d

TEST CONCENTRATIONS
- Range finding study
- Test concentrations: control, 0.2, 2.0 and 20.0 g/kg substance, solvent: Isopropanol
- Results used to determine the conditions for the definitive study: 20 and 30% mortalities after 14 days in all concentrations including control (was explained with residual solvent)

Nominal and measured concentrations:

nominal: 0 and 20000 mg/kg soil

Reference substance (positive control):

yes

Remarks:

Chloracetamid

Results and discussion

Effect concentrations

Duration:

14 d

Dose descriptor:

LC50

Effect conc.:

> 20 000 mg/kg soil dw

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality

Details on results:

- Mortality at end of exposure period: 0% after 14 days at 20000 mg/kg soil and control

Results with reference substance (positive control):

- Results with reference substance valid? yes
- Relevant effect levels: Concentrations used: control, 0.1, 1.0 and 10 mg/kg soil; 60% in 14 days at 10 mg/kg, 20% mortality at 1.0 mg/kg and 0% mortality at 0.1 mg/kg substrate. LC50(14d) = 6.0 mg/kg dw, NOEC(14d) = 0.1 mg/kg dw
- Total mass of adults at beginning of test: 344.9 mg ± 32.8 mg