Registration Dossier
Registration Dossier
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EC number: 255-473-8 | CAS number: 41642-51-7
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1990
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
Data source
Reference
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- N-[2-[(2,6-dicyano-4-nitrophenyl)azo]-5-(diethylamino)phenyl]acetamide
- EC Number:
- 255-473-8
- EC Name:
- N-[2-[(2,6-dicyano-4-nitrophenyl)azo]-5-(diethylamino)phenyl]acetamide
- Cas Number:
- 41642-51-7
- Molecular formula:
- C20H19N7O3
- IUPAC Name:
- N-[2-[(2,6-dicyano-4-nitrophenyl)azo]-5-(diethylamino)phenyl]acetamide
- Test material form:
- solid: particulate/powder
- Details on test material:
- Terasil Blau BG conc.
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- no
- Details on test solutions:
- test item solved in water
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- ca. 23°C
- pH:
- 8.0 - 8.2
- Dissolved oxygen:
- 89 - 93%
- Nominal and measured concentrations:
- 100, 300 and 1000 mg/L
- Details on test conditions:
- - No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 1 - Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- no mortality ocured in any concentration
Any other information on results incl. tables
- Sublethal observations / clinical signs:
concentration
[mg/L]survived fish 1h 4h 24h 48h 96h 100.0 10 10 10 10 10 300.0 10 10 10 10 10 1000.0 10 10 10 10 10
Applicant's summary and conclusion
- Conclusions:
- The 96 h LC50 to Zebra-fish was determined to be > 1000.0mg/L
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