Registration Dossier
Registration Dossier
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EC number: 943-524-3 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- other: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Study period:
- June 4, 1976
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Remarks:
- The endpoint was evaluated by means of Read Across approach. THe complete justification is attached at section 13
- Qualifier:
- according to guideline
- Guideline:
- other: Ciba Geigy AG internal method 58
- Deviations:
- not specified
- Principles of method if other than guideline:
- This method is designed to evaluate the acute bacterial toxicity to sewage sludge or isolated suspended bacteria
under aerobe conditions. - GLP compliance:
- no
- Analytical monitoring:
- not specified
- Test organisms (species):
- activated sludge
- Details on inoculum:
- 0.1 ml of dilutions are mixed with 4.5 ml of Nutrient broth in a test tube.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 5 d
- Duration:
- 5 d
- Dose descriptor:
- LOEC
- Effect conc.:
- > 300 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: opacity
- Validity criteria fulfilled:
- not specified
- Conclusions:
- BST> 300 mg/l
- Executive summary:
The substance has been tested for bacteria growth inhibition according to internal method 58. The substance shows a BST> 300 mg/l.
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- September 1982
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
- Remarks:
- The endpoint was evaluated by means of Read Across approach. THe complete justification is attached at section 13
- Qualifier:
- according to guideline
- Guideline:
- ETAD Fermentation Tube Method
- Deviations:
- not specified
- GLP compliance:
- no
- Analytical monitoring:
- not specified
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 30 min
- Duration:
- 30 min
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Validity criteria fulfilled:
- not specified
- Conclusions:
- EC50 > 100 mg/l
- Executive summary:
The substance has been tested for bacteria growth inhibition test. The substance shows a EC50 > 100 mg/l.
Referenceopen allclose all
Description of key information
IC50 > 100 mg/l
Key value for chemical safety assessment
- EC50 for microorganisms:
- 100 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
