Registration Dossier
Registration Dossier
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EC number: - | CAS number: 1309389-73-8
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2016-03-16
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 2008
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- 2015-12-16
- Type of method:
- column elution method
- Key result
- Water solubility:
- 0.124 mg/L
- Temp.:
- 20 °C
- pH:
- 5
- Remarks on result:
- other: n = 10
- Conclusions:
- Interpretation of results: slightly soluble (0.1-100 mg/L)
According to OECD Guideline 105 (1995) and Regulation (EC) No 440/2008 Method A.6., the water solubility of the substance is 0.124 mg/L at 20 °C and pH 5.
Reference
Results for determination of water solubility
Experiment number |
Flow rate [mL/min] |
Sample number |
pH |
Measured concentration of test item in the sample [mg/L] |
Water solubility mean value ± SD [mg/L] |
RSD [%] |
1 |
0.69 |
1 2 3 4 5 |
5 5 5 5 5 |
0.122 0.125 0.115 0.127 0.140 |
0.126 ± 0.009 |
7.23 |
2 |
0.35 |
6 7 8 9 10 |
5 5 5 5 5 |
0.123 0.121 0.114 0.127 0.126 |
0.122 ± 0.005 |
4.20 |
Overall Mean: |
0.124 |
- |
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Description of key information
The water solubility of the substance is 0.124 mg/L at 20 °C and pH 5.
Key value for chemical safety assessment
- Water solubility:
- 0.124 mg/L
- at the temperature of:
- 20 °C
Additional information
The water solubility of the substance was performed in accordance with the OECD Guideline 105 under GLP, using the column elution method. The substance was analytically verified using HPLC-UV.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
