Registration Dossier
Registration Dossier
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EC number: 247-117-5 | CAS number: 25583-20-4
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is highly insoluble in water, hence indicating that aquatic toxicity is unlikely to occur
Reference
Description of key information
In accordance with column 2 of REACH Annex VIII, the activated sludge respiration inhibition test does not need to be conducted as there are mitigating factors indicating that microbial toxicity is unlikely to occur. With regard to a study according to OECD 29, for TiN a water solubility of 23.8 µg Ti/L (100 mg loading, pH 6, 7 days) was determined. In addition, under the conditions of OECD guidelines 201, 202 and 203, respectively, measured Ti concentrations were below 2 µg/L at test initiation and at test termination in all control and test exposures. Based on water solubility limitations, tests on toxicity against microorganisms are scientifically not justified.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
