Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 210-441-2 | CAS number: 615-66-7
Endpoint summary
Administrative data
Description of key information
Transport and distribution
Adsorption / desorption
The Soil Adsorption Coefficient (Koc) of 2-chloro-p-phenylenediamine was estimated using the EPI suite KOCWIN Program (v2.00). The Soil Adsorption Coefficient (Koc) of 2-chloro-p-phenylenediamine was estimated as 55.39 L/kg (log Koc = 1.7434) by means of MCI method. The results indicate that the chemical 2-chloro-p- phenylenediamine (CAS No.615-66-7) is likely to to show low tendency of sorption to soil and sediment and show moderate migration potential to groundwater.
Additional information
Transport and distribution
Adsorption / desorption
Various adsorption studies for the target substance 2-chloro-p-phenylenediamine (CAS No.615-66-7) and for its read across substances 3-chloroaniline (CAS No.- 108-42-9) and 3,4-dichloroaniline (CAS No.- 95-76-1) by considering its structure-activity relationships, were summarized as follows:
The Soil Adsorption Coefficient (Koc) of 2-chloro-p-phenylenediamine was estimated using the EPI suite KOCWIN Program (v2.00). The Soil Adsorption Coefficient (Koc) of 2-chloro-p-phenylenediamine was estimated as 55.39 L/kg (log Koc = 1.7434) by means of MCI method. The results indicate that the chemical 2-chloro-p-phenylenediamine (CAS No.615-66-7) is likely to to show low tendency of sorption to soil and sediment and show moderate migration potential to groundwater.
Another Predicted data for soil adsorption coefficient of 2-chloro-p-phenylenediamine (CAS No.615-66-7) is generated using the ACD/Labs Percepta Platform - PhysChem Module. The soil adsorption coefficient i.e Koc of test substance 2-chloro-p-phenylenediamine was estimated to be 77.11 (Log Koc = 1.88) and 94.22 (Log Koc = 1.94) at pH 5.5 and 7.4 and at temperature 25 deg C. The results indicate that the chemical 2-chloro-p-phenylenediamine (CAS No.615-66-7) is likely to show low tendency of sorption to soil and sediment and show moderate migration potential to groundwater.
Based on the study from an authoritative database [HSDB(Hazardous Substances Data Bank) (2017)], an estimated adsorption coefficient (Koc) value of 250, determined from a log Kow of 1.88 and a regression-derived equation, indicates that 3-chloroaniline (CAS No.- 108-42-9) is expected to have moderate mobility in soil.
Moreover, based on the study from a same authoritative database [HSDB(Hazardous Substances Data Bank) (2017)], a Koc value of 193 (log Koc= 2.29) was measured during a batch adsorption test with a silt loam soil. According to a classification scheme, this Koc value suggests that 3,4-dichloroaniline (CAS No.- 95-76-1) is expected to have moderate mobility in soil.
Thus based on the above studies for target substance 2-chloro-p-phenylenediamine and the read across substance and by applying weight of evidence approach, it can be concluded that the chemical 2-chloro-p-phenylenediamine (CAS No.615-66-7) is likely to show low to moderate tendency of sorption to soil and sediment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
