Registration Dossier
Registration Dossier
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EC number: 249-942-6 | CAS number: 29901-62-0
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
No experimental data about genetic toxicity of the test substance are available. But there are several data from study reports, public journals and other literature sources which describe and characterize sulfanilic acid as well as the sodium salt.It is acceptable to derive genetic toxicity from experimental data of sulfanilic acid and the sodium analogue. The potassium salt as well as the sodium salt dissociates in aqueous solution in free sulfanilic acid and the respective ions.
Sulfanilic acid was tested in several Ames tests and found to be negative in this test system. Moreover, there are no strucutral hints for mutagenic potential. Therefore, the test substance is considered to be not mutagenic in Ames test.
Short description of key information:
No experimental data about genetic toxicity of the test substance are available. Sulfanilic acid was tested in several Ames tests and found to be negative in this test system. Moreover, there are no strucutral hints for mutagenic potential. Therefore, the test substance is considered to be not mutagenic in Ames test.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Dangerous Substance Directive (67/548/EEC)
The available studies are considered reliable and suitable for classification purposes under 67/548/EEC. As a result the substance is not considered to be classified for genotoxicity under Directive 67/548/EEC, as amended for the 28th time in Directive 2001/59/EC.
Classification, Labelling, and Packaging Regulation (EC) No. 1272/2008
The available experimental test data are reliable and suitable for classification purposes under Regulation 1272/2008. As a result the substance is not considered to be classified for genotoxicity under Regulation (EC) No. 1272/2008.
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