Registration Dossier
Registration Dossier
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EC number: 207-622-3 | CAS number: 485-71-2
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.06 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.605 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.006 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 24.02 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 2.402 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 24.02 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Additional information
Cinchonidine hydrochloride was tested in a static Daphnia magna, Acute Immobilisation Test according to the OECD Guideline 202 for 48 h. Five nominal concentrations between 26 and 100 mg/L were used. The EC50 of cinchonidine hydrochloride is 68.09 mg/L for Daphnia magna during the test period of 48 h. According to this, the EC50 of cinchonidine is 60.5 mg/L.
Conclusion on classification
The experimentally determined EC50 of cinchonidine for invertebrates is > 1 mg/L. According to CLP 1272/2008 criteria for acute aquatic toxicity, cinchonidine does not need to be classified.
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