Registration Dossier
Registration Dossier
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EC number: 284-660-7 | CAS number: 84961-70-6
Endpoint summary
Administrative data
Description of key information
Additional information
Studies show that HAB is generally considered to be non-toxic to aquatic organisms at the limits of water solubility. Short-term fish studies show LC50 values greater than the Water Accommodated Fraction (WAF) or the highest nominal concentrations. An extended (14-day) acute study with fish exposed to LAB, the most water soluble component of HAB, resulted in a NOEC greater than 10 µg/L (0.010 mg/L), the highest concentration tested using a water accommodated fraction. Acute studies with Daphnia also demonstrated that EC50 values were greater than the limits of water solubility. A 21-day chronic study with Daphnia exposed to LAB, the most water soluble component of HAB, still resulted in an EC50 of 0.012 mg/L and a NOEC of 0.0075 mg/L. While this latter value exceeds the criteria, it was accomplished only by testing the most water soluble component of HAB and then further artificially enhancing solubility through use of acetone as a solvent.
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