Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 229-177-4 | CAS number: 6422-99-7
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Sebacid acid, compound with hexane-1,6-diamine is readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
The 2015 experimental study was performed in compliance with GLP according to OECD 301B method. This study was scored as Klimisch 1 and concludes that sebacic acid, compound with hexane-1,6-diamine is readily biodegradable. Another study, performed in 2013, was available. It is GLP-compliant and performed according to OECD 301D. However, this study was scored as Klimisch 2 due to the fact that a discontinuity was observed on the biodegradation curves (see the Endpoint Study Record entitled "Biodeg SS V2 2013 HARLAN" for further details). This study concludes that sebacic acid, compound with hexane-1,6-diamine is not readily biodegradable. It has to be considered that ready biodegradability tests as OECD 301 studies presents very stringent experimental conditions: the test substance is the only source of carbon in the test medium, inoculum is present at low concentrations and the test duration is limited to 28 days. Therefore and in accordance with ECHA Guidance R7b, consistent positive test results should generally supersede negative test results. For this reason and considering the difference of reliability between both studies, the 2015 study was flagged as the key study and the 2013 study as the supporting study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
