Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
repeated dose toxicity: other route
Adequacy of study:
other information

Data source

Reference
Title:
No information
Author:
Bernhard, A.M. et al. Toxicol. Lett. 45, 271-280 (1989)

Materials and methods

Principles of method if other than guideline:
Method: other: 5 rats/group, collection of 24 h urine after last injection, determination of urinariy concentration of albumin and beta-2-microglobulin
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Automatically generated during migration to IUCLID 6, no data available
IUPAC Name:
Automatically generated during migration to IUCLID 6, no data available
Details on test material:
IUCLID4 Test substance: other TS: cyclopentane, analytical grade giveb in cornoil

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
female

Administration / exposure

Route of administration:
intraperitoneal
Duration of treatment / exposure:
2 weeks
Frequency of treatment:
5 times/week
Doses / concentrations
Remarks:
Doses / Concentrations:
1 500 mg/d
Control animals:
yes, concurrent vehicle
Details on study design:
Post-exposure period: no data

Results and discussion

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion