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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study according EU/OECD guideline.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chloro-4-methanesulfonyl-3-methylbenzoic acid
EC Number:
600-786-0
Cas Number:
106904-09-0
Molecular formula:
C9H9ClO4S
IUPAC Name:
2-chloro-4-methanesulfonyl-3-methylbenzoic acid

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
other: activated sludge, domestic (adaptation not specified)

Study design

Test type:
static
Water media type:
freshwater
Total exposure duration:
3 h

Results and discussion

Effect concentrations
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate

Applicant's summary and conclusion

Executive summary:

A study was performed to assess the toxicity of the test substance to bacteria. The study was conducted in accordance with Council Directive 67/548/EEC; Annex V, Method C.11 "Activated sludge respiration inhibition" (1988). This test method is equal to OECD Guideline 209 (1984). The activated sludge was exposed to the test substance at different concentrations. The respiration rate of each mixture was determined after aeration periods of 3 hours. The testsubstance showed 0.00 % respiration inhibition of activated sludge at a test item concentration of 1000 mg/L. The EC50 is higher than 1000 mg/L. The effectvalue related to nominal concentration, since no analytical monitoring was performed