Registration Dossier
Registration Dossier
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EC number: 200-834-7 | CAS number: 75-04-7
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The assessment of the chronic aquatic toxicity is based on the 7 d Ceriodaphnia study. No chronic test on fish is deemed necessary.
Key value for chemical safety assessment
Additional information
A chronic toxicity test on fish does not need to be conducted due to the facts that
- the substance is not classified according to 67/548/EEC
- the substance does not have a potential to bioaccumulate nor is it considered as a PBT/vPvB substance
- taking into consideration results from short-term toxicity tests on fish, Daphnia and algae there is a high probability that the most sensitive species (algae) has already been examined and that a further long-term result from fish would not be lower than the data already available.
Therefore, and for reasons of animal welfare, a chronic test on fish is not provided.
Further, considering the results from a chronic 7d study on Ceriodaphnia resulting in a NOEC of 3.2 mg/L and the higher sensitivity of daphnids to the test substance in the acute test (EC50 of 7.9 mg/L compared to the acute fish test LC50 of 240 mg/L) it is not to be expected, that a chronic test on fish will reveal any additional information on the chronic aquatic toxicity of the test substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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