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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
other: Test material identity does not conform to the MWCNT meeting the form described in section 4.5 of the IUCLID dossier or cannot be proved beyond reasonable doubt

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Genotoxicity and Cyto-toxicity ofMulti-wall Carbon Nanotubes in Cultured Chinese Hamster Lung Cells in Comparison with Chrysotile A Fibers
Author:
Asakura, M. et al.
Year:
2010
Bibliographic source:
Journal of Occupational Health 52, 155-166
Reference Type:
publication
Title:
Multi-walled carbon nanotubes: Lack of mutagenic activity in the bacterial reverse mutation assay
Author:
Di Sotto, A. et al.
Year:
2009
Bibliographic source:
Toxicology Letters 184, 192-197
Reference Type:
publication
Title:
Copper Oxide Nanoparticles Are Highly Toxic: A Comparison between Metal Oxide Nanoparticles and Carbon Nanotubes
Author:
Karlsson, H.L. et al.
Year:
2008
Bibliographic source:
Chem. Res. Toxicol. 21, 1726-1732
Reference Type:
publication
Title:
Carbon Nanotubes Induce Oxidative DNA Damage in RAW264.7 Cells
Author:
Migliore, L. et al.
Year:
2010
Bibliographic source:
Environmental and Molecular Mutagenesis 51, 294-303
Reference Type:
publication
Title:
Oxidative and molecular interactions of multi-wall carbon nanotubes (MWCNT) in normal and malignant human mesothelial cells
Author:
Pacurari, M. et al.
Year:
2008
Bibliographic source:
Nanotoxicology 2, 155-170
Reference Type:
publication
Title:
Induction of Apoptosis in Rat Lung Epithelial Cells by Multi-walled Carbon Nanotubes
Author:
Ravichandran, P. et al.
Year:
2009
Bibliographic source:
J. Biochem. Molecular Toxicology 23, 333-344
Reference Type:
publication
Title:
Relating the physico-chemical characteristics and dispersion of multiwalled carbon nanotubes in different suspension media to their oxidative reactivity in vitro and inflammation in vivo
Author:
Rothen-Rutishauser, B. et al.
Year:
2010
Bibliographic source:
Nanotoxicology 4, 331-342
Reference Type:
publication
Title:
Airway barrier dysfunction induced by exposure to carbon nanotubes in vitro: which role for fiber length?
Author:
Rotoli, B.M. et al.
Year:
2009
Bibliographic source:
Human & Experimental Toxicology 28, 377-385
Reference Type:
publication
Title:
Non-functionalized multi-walled carbon nanotubes alter the paracellular permeability of human airway epithelial cells
Author:
Rotoli, B.M. et al.
Year:
2008
Bibliographic source:
Toxicology Letters 178, 95-102
Reference Type:
publication
Title:
Potential in vitro effects of carbon nanotubes on human aortic endothelial cells
Author:
Walker, V.G. et al.
Year:
2009
Bibliographic source:
Toxicology and Applied Pharmacology 236, 319-328

Materials and methods

Results and discussion

Applicant's summary and conclusion