Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

Currently viewing:

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Peer reviewed data

Data source

Reference
Reference Type:
review article or handbook
Title:
Documentation of the Threshold Limit Values and Biological Exposure Indices.
Author:
American Conference of Governmental Industrial Hygienists, Inc.
Year:
1991
Bibliographic source:
6th ed. Volumes I, II, III. Cincinnati, OH: ACGIH

Materials and methods

Principles of method if other than guideline:
No data

Test material

Constituent 1
Chemical structure
Reference substance name:
Chloroacetyl chloride
EC Number:
201-171-6
EC Name:
Chloroacetyl chloride
Cas Number:
79-04-9
Molecular formula:
C2H2Cl2O
IUPAC Name:
2-chloroacetyl chloride

Test animals

Species:
rat

Administration / exposure

Route of administration:
inhalation
Duration of exposure:
4 h

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
1 000 ppm

Applicant's summary and conclusion

Interpretation of results:
Toxicity Category III
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
LC50 Rat inhalation 1000 ppm/4 hr
Executive summary:

LC50 Rat inhalation 1000 ppm/4 hr