Registration Dossier
Registration Dossier
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EC number: 606-097-1 | CAS number: 186817-80-1
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Water solubility:
- ca. 0.429 g/L
- Temp.:
- 20 °C
- pH:
- ca. 6.5
- Remarks on result:
- other: The pH of the aqueous sample was determined after 72 hours stirring.
- Details on results:
- The results for the samples taken at 24, 48 and 72 hours are given in Table 1 below.
The maximum difference (MD) of the concentrations determined in the 24, 48 and 72 hour test samples was 15 %. According to the guidelines, the water solubility of the test substance is given as the mean value of the analysed concentrations.
In the pre-treated sample from the bank water mixture a small response was observed, the maximum contribution was 0.06 %, thus neglegible. - Conclusions:
- 2-Ethylhexyl-S-lactate is moderately soluble in water.
- Executive summary:
The flask method was chosen for the determination of the water solubility of PURASOLV®EHL (2 -ethylhexyl-S-lactate). The water solubility of the test substance at 20 °C was 0.429 g/L. The pH of the aqueous sample after 72 hours stirring was 6.5.
Reference
Table 1. Main study - water solubility of PURASOLV®EHL (2-ethylhexyl-S-lactate).
Stirring time (hours) |
Analysed concentration (g/l) |
Mean (g/l) |
MD (%) |
pH |
24 |
0.428 |
0.429 |
1.8 |
6.8 |
48 |
0.434 |
|
|
6.7 |
72 |
0.426 |
|
|
6.5 |
Description of key information
The water solubility of 2 -ethylhexyl-S-lactate, determined using the flask method, is 0.429 g/L at 20 °C. The pH of the aqueous sample after 72 hours stirring was 6.5.
Key value for chemical safety assessment
- Water solubility:
- 0.429 g/L
- at the temperature of:
- 20 °C
Additional information
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