Registration Dossier
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EC number: 203-983-6 | CAS number: 112-54-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The test substance was assessed for short-term toxicity to fish according to OECD guideline 203. The LC₅₀ of 2.6 mg/L (nominal test concentration) exceeds the water solubility of this substance (1.3mg/L) and can be explained by the use of a surfactant in the preparation of the test solutions. Such EC50 levels are not considered environmentally relevant and cannot be used for risk assessment purposes. Since no effects were observed up to a nominal concentration of 2.0 mg/L, 1.5 times the water solubility limit, the substance is considered not to exhibit toxic effects up to the limit of solubility for classification purposes.
Key value for chemical safety assessment
Additional information
The test substance was assessed for short-term toxicity to fish according to OECD guideline 203. Rainbow Trout (Oncorhynchus mykiss) were exposed for 96 hours under semi-static conditions to 5 nominal concentrations of dodecanal in Tween 80 with test substance and vehicle concentrations ranging from 1.2 to 10 mg/L. The 96-hour LC50 value was determined to be 2.6 mg/L. The no-mortality concentration was 2.0 mg/L.
The measured solubility limit of the test substance in pure water has been determined as 1.3 mg/L. No effects were observed up to a nominal concentration of 2.0 mg/L, 1.5 times the water solubility limit. Therefore, any mortality or effects observed are considered due to physical effects due to the surfactant artificially maintaining the test substance in an emulsion that was stable under the conditions of the study but not possible to maintain under environmental conditions. In conclusion this study showed that there were no toxic effects at the limit of solubility.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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