Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 911-369-0 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The Ready Biodegradability of Cyclacet was determined by the Manometric Respirometry Test according to the OECD Guidelines for Testing of Chemicals, Method No. 301 F. The concentration tested was 100 mg/l Cyclacet, with an activated sludge concentration of 30 mg/l. Cyclacet undergoes only 10 % biodegradation after 28 days in the test conditions. Thus, Cyclacet should be regarded as not readily biodegradable under the conditions in this test.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
In addition to the ready biodegradation of Cyclacet also the ready biodegradability of Cyclabute is presented because Cyclacet will follow a similar pathway as Cyclabute.Therefore the Cyclabute ready biodegradation test is summarised here to support the DT50 information, which is discussed in the Biodegradation Overall Endpoint summary together with the analogue justification.
Cyclabute's ready biodegradability test
The ready biodegradability of Cyclabute was determined according to OECD guideline 301F (manometric respirometry test). Cyclabute undergoes 22% biodegradation after 28 days (23% biodegradation after 60 days, 23% biodegradation after 61 days) under the test conditions. The curve obtained with the reference substance alone and with Cyclabute + reference substance shows no toxic effect of Cyclabute to the micro-organisms at the test concentration (100 mg/L). Cyclabute should be regarded as not readily biodegradable under the conditions of this test. After the 61 days the primary degradation products were determined as well as their log Kow values. No Cyclabute was found and Cyclabute's alcohol was the main metabolite (82%) and Cyclabute's ketone the minor metabolite (18%). Their log Kows were 2.4 and 3.2, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
