Registration Dossier
Registration Dossier
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EC number: 226-551-9 | CAS number: 5423-22-3
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
In a 3 h activated sludge respiration inhibition study conducted according to OECD guideline 209, microorganisms in activated sludge were exposed to Guanidine phosphate (1:1). The NOEC could not be determined and the EC50 was >1000 mg/L. The study is considered to be reliable with restrictions since the pH was not adjusted in the highest test concentration (1000 mg/L). Nonetheless, the test is deemed acceptable as the EC50 exceeded 1000 mg/L.
Key value for chemical safety assessment
Additional information
In a 3 h activated sludge respiration inhibition study conducted according to OECD guideline 209, microorganisms in activated sludge were exposed to Guanidine phosphate (1:1) at the following nominal concentrations: 0 (blank control), 10, 100 and 1000 mg/L. The test substance significantly inhibited the respiration rate at a concentration of 1000 mg/L. The NOEC could not be determined and the EC50 was >1000 mg/L. The study is considered to be reliable with restrictions since the pH was not adjusted in the highest test concentration (1000 mg/L). Nonetheless, the test is deemed acceptable as the EC50 exceeded 1000 mg/L.
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