Registration Dossier
Registration Dossier
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EC number: 931-335-9 | CAS number: 90622-74-5
Solubility in organic solvents / fat solubility
Administrative data
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- July 26, 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: EU test method L383 A/54-62 (EEC A.6)
- Deviations:
- no
- Principles of method if other than guideline:
- The flask method is used for determination of 1-octanol solubility. In this method, the substance dissolved in 1-octanol at a temperature somewhat above the test temperature. When saturation is achieved the mixture is cooled and kept at the test temperature, stirring as long as necessary to reach equilibrium. Subsequently, the mass concentration of the substance in the supernatant aqueous solution, which must not contain any undissolved particles, is determined by a suitable analytical method.
- GLP compliance:
- no
Test material
- Reference substance name:
- Amides, C12-18(even-numbered) and C18(unsatd.), N,N-bis(hydroxyethyl)
- EC Number:
- 931-335-9
- Cas Number:
- 90622-74-5
- Molecular formula:
- not applicable
- IUPAC Name:
- Amides, C12-18(even-numbered) and C18(unsatd.), N,N-bis(hydroxyethyl)
- Test material form:
- liquid: viscous
- Remarks:
- Light yellow
Constituent 1
Results and discussion
Solubility in organic solvents / fat solubility
- Medium:
- n-octanol
- Remarks:
- 1-octanol
- Remarks on result:
- other: Test substance is miscible in 1-octanol in all proportions
- Details on results:
- The test material is mixable with 1-octanol in all proportions
Any other information on results incl. tables
Preliminary test:
For this purpose, 0.1 g of the test material was melted and weighed in and 0.1, 0.5, 1.0, 2.0 and 10.0 g of 1-octanol were added to each weighted sample. The test material was completely solved giving clear solutions.
Applicant's summary and conclusion
- Conclusions:
- Under the study conditions, the test substance was miscible in 1-octanol in all proportions.
- Executive summary:
A study was conducted to determine the 1-octanol solubility of the test substance, C12-18 and C18-unsatd. DEA, according to EU Method A.6. Under the study conditions, the test substance was miscible in 1-octanol in all proportions (Frishmann, 2010).
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