1,1-dimethylprop-3-ynylamine

Guidance on Safe Use

First-aid measures

Description of first aid measures

General advice: First Aid responders should pay attention to self-protection and use the recommended protective clothing (chemical resistant gloves, splash protection).

Inhalation: Move person to fresh air. If person is not breathing, call an emergency responder or ambulance, and then give artificial respiration; if by mouth to mouth use rescuer protection (pocket mask etc). Call a poison control center or doctor for treatment advice. If breathing is difficult, oxygen should be administered by qualified personnel.

Skin Contact: Take off contaminated clothing. Rinse skin immediately with plenty of water for 15-20 minutes. Call a poison control center or doctor for treatment advice. Suitable emergency safety shower facility should be immediately available.

Eye Contact: Wash immediately and continuously with flowing water for at least 30 minutes. Remove contact lenses after the first 5 minutes and continue washing. Obtain prompt medical consultation, preferably from an ophthalmologist. Suitable emergency eye wash facility should be immediately available.

Ingestion: Call a poison control center or doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by the poison control center or doctor. Never give anything by mouth to an unconscious person.

Most important symptoms and effects, both acute and delayed

Aside from the information found under Description of first aid measures (above) and Indication of immediate medical attention and special treatment needed (below), no additional symptoms and effects are anticipated.

Indication of immediate medical attention and special treatment needed

Maintain adequate ventilation and oxygenation of the patient. May cause asthma-like (reactive airways) symptoms. Bronchodilators, expectorants, antitussives and corticosteroids may be of help. Respiratory symptoms, including pulmonary edema, may be delayed. Persons receiving significant exposure should be observed 24-48 hours for signs of respiratory distress. Chemical eye burns may require extended irrigation. Obtain prompt consultation, preferably from an ophthalmologist. If burn is present, treat as any thermal burn, after decontamination. Exposure to amine vapors may cause minor transient edema of the corneal epithelium (glaucopsia) with blurred vision, blue haze and halos around bright objects. Effects disappear in a few hours and temporarily reduce ability to drive vehicles. Due to irritant properties, swallowing may result in burns/ulceration of mouth, stomach and lower gastrointestinal tract with subsequent stricture. Aspiration of vomitus may cause lung injury. Suggest endotracheal/esophageal control if lavage is done. Probable mucosal damage may contraindicate the use of gastric lavage. No specific antidote. Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient. Have the Safety Data Sheet, and if available, the product container or label with you when calling a poison control center or doctor, or going for treatment.

Excessive exposure may aggravate preexisting asthma and other respiratory disorders (e.g. emphysema, bronchitis, reactive airways dysfunction syndrome).

Fire-fighting measures

Extinguishing Media

Water fog or fine spray. Dry chemical fire extinguishers. Carbon dioxide fire extinguishers. Foam.  Do not use direct water stream. Straight or direct water streams may not be effective to extinguish fire. Alcohol resistant foams (ATC type) are preferred. General purpose synthetic foams (including AFFF) or protein foams may function, but will be less effective.

Special hazards arising from the substance or mixture

Hazardous Combustion Products: During a fire, smoke may contain the original material in addition to combustion products of varying composition which may be toxic and/or irritating. Combustion products may include and are not limited to: Nitrogen oxides. Carbon monoxide. Carbon dioxide Ammonia.

Unusual Fire and Explosion Hazards: Container may rupture from gas generation in a fire situation. Electrically ground and bond all equipment. Flammable mixtures of this product are readily ignited even by static discharge. Vapors are heavier than air and may travel a long distance and accumulate in low lying areas. Ignition and/or flash back may occur. Flammable mixtures may exist within the vapor space of containers at room temperature. Flammable concentrations of vapor can accumulate at temperatures above flash point. Dense smoke is produced when product burns.

Advice for firefighters

Fire Fighting Procedures: Keep people away. Isolate fire and deny unnecessary entry. Stay upwind. Keep out of low areas where gases (fumes) can accumulate. Water may not be effective in extinguishing fire. Use water spray to cool fire exposed containers and fire affected zone until fire is out and danger of reignition has passed. Fight fire from protected location or safe distance. Consider the use of unmanned hose holders or monitor nozzles. Immediately withdraw all personnel from the area in case of rising sound from venting safety device or discoloration of the container. Burning liquids may be extinguished by dilution with water. Do not use direct water stream. May spread fire. Eliminate ignition sources. Move container from fire area if this is possible without hazard. Burning liquids may be moved by flushing with water to protect personnel and minimize property damage. Contain fire water run-off if possible. Fire water run-off, if not contained, may cause environmental damage.

Special Protective Equipment for Firefighters: Wear positive-pressure self-contained breathing apparatus (SCBA) and protective fire fighting clothing (includes fire fighting helmet, coat, trousers, boots, and gloves). Avoid contact with this material during fire fighting operations. If contact is likely, change to full chemical resistant fire fighting clothing with self-contained breathing apparatus. If this is not available, wear full chemical resistant clothing with self-contained breathing apparatus and fight fire from a remote location. For protective equipment in post-fire or non-fire clean-up situations, refer to the relevant sections.

Accidental release measures

Personal precautions, protective equipment and emergency procedures: No smoking in area. Evacuate area. Only trained and properly protected personnel must be involved in clean-up operations. Keep personnel out of low areas. Keep up wind of spill. Ventilate area of leak or spill. Eliminate all sources of ignition in vicinity of spill or released vapor to avoid fire or explosion. Vapor explosion hazard. Keep out of sewers. For large spills, warn public of downwind explosion hazard. Check area with combustible gas detector before reentering area. Ground and bond all containers and handling equipment

Environmental precautions: Prevent from entering into soil, ditches, sewers, waterways and/or groundwater. See Section 12, Ecological Information. Spills or discharge to natural waterways is likely to kill aquatic organisms.

Methods and materials for containment and cleaning up: Ground and bond all containers and handling equipment. Pump with explosion-proof equipment. If available, use foam to smother or suppress. Contain spilled material if possible. Small spills: Absorb with materials such as: Clay. Dirt. sand. Sweep up. Collect in suitable and properly labeled containers. Large spills: Contact Dow AgroSciences for clean-up assistance.

Handling and storage

Risk Management Measures: This substance is handled under Strictly Controlled Conditions in accordance with REACH Regulation Article 17(3) for on-site isolated intermediates and ECHA Guidance on Intermediates, version 2-December 2010 (Reference: ECHA-2010-G-17-EN). The substance is synthesised only in one site in the EU, with the Manufacturer and the User being the same legal entity. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at the manufacturing and use site.

General Handling: Keep out of reach of children. Keep away from heat, sparks and flame. Do not get in eyes, on skin, on clothing. Do not swallow. Avoid breathing vapor or mist. Wash thoroughly after handling. Keep container closed. Use only with adequate ventilation. No smoking, open flames or sources of ignition in handling and storage area. Electrically bond and ground all containers and equipment before transfer or use of material. Use of non-sparking or explosion-proof equipment may be necessary, depending upon the type of operation. Containers, even those that have been emptied, can contain vapors. Do not cut, drill, grind, weld, or perform similar operations on or near empty containers. Never use air pressure for transferring product. Vapors are heavier than air and may travel a long distance and accumulate in low lying areas. Ignition and/or flash back may occur.

Conditions for safe storage, including any incompatibilities

Store in a dry place. Store in original container. Keep container tightly closed when not in use. Do not store near food, foodstuffs, drugs or potable water supplies. Minimize sources of ignition, such as static build-up, heat, spark or flame. Keep container closed. Flammable mixtures may exist within the vapor space of containers at room temperature.

Specific end uses

For use as chemical intermediate

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

Risk Management Measures: This substance is handled under Strictly Controlled Conditions in accordance with REACH Regulation Article 17(3) for on-site isolated intermediates and ECHA Guidance on Intermediates, version 2-December 2010 (Reference: ECHA-2010-G-17-EN). The substance is synthesised only in one site in the EU, with the Manufacturer and the User being the same legal entity. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at the manufacturing and use site.

Eye/Face Protection: Use chemical goggles. Chemical goggles should be consistent with EN 166 or equivalent. If exposure causes eye discomfort, use a full-face respirator.

Skin Protection: Use protective clothing chemically resistant to this material. Selection of specific items such as face shield, boots, apron, or full body suit will depend on the task.

Hand protection: Use chemical resistant gloves classified under Standard EN374: Protective gloves against chemicals and micro-organisms. Examples of preferred glove barrier materials include: Chlorinated polyethylene. Polyethylene. Ethyl vinyl alcohol laminate (“EVAL”). Examples of acceptable glove barrier materials include: Butyl rubber. Natural rubber (“latex”). Neoprene. Nitrile/butadiene rubber (“nitrile” or “NBR”). Polyvinyl chloride (“PVC” or “vinyl”). Viton. When prolonged or frequently repeated contact may occur, a glove with a protection recommended. When only brief contact is expected, a glove with a protection class of 3 or higher (breakthrough time greater than 60 minutes according to EN 374) is recommended.

NOTICE: The selection of a specific glove for a particular application and duration of use in a workplace should also take into account all relevant workplace factors such as, but not limited to: Other chemicals which may be handled, physical requirements (cut/puncture protection, dexterity, thermal protection), potential body reactions to glove materials, as well as the instructions/specifications provided by the glove supplier.

Respiratory Protection: Respiratory protection should be worn when there is a potential to exceed the exposure limit requirements or guidelines. If there are no applicable exposure limit requirements or guidelines, use an approved respirator. Selection of air-purifying or positive-pressure supplied-air will depend on the specific operation and the potential airborne concentration of the material. For emergency conditions, use an approved positive-pressure self-contained breathing apparatus. Use the following CE approved air-purifying respirator: Organic vapor, acid gas, SO2, ammonia cartridge with a particulate pre-filter, type ABEKP2.

Ingestion: Avoid ingestion of even very small amounts; do not consume or store food or tobacco in the work area; wash hands and face before smoking or eating.

Ventilation: Use engineering controls to maintain airborne level below exposure limit requirements or guidelines. If there are no applicable exposure limit requirements or guidelines, use only with adequate ventilation. Local exhaust ventilation may be necessary for some operations.

Stability and reactivity

Reactivity

No dangerous reaction known under conditions of normal use.

Chemical stability

Thermally stable at typical use temperatures.

Possibility of hazardous reactions

Polymerization will not occur.

Conditions to Avoid: Exposure to elevated temperatures can cause product to decompose. Generation of gas during decomposition can cause pressure in closed systems. Avoid static discharge.

Incompatible Materials: Avoid contact with: Acid chlorides. Strong acids. Strong oxidizers. Copper. Aluminum.

Hazardous decomposition products

Decomposition products depend upon temperature, air supply and the presence of other materials. Toxic gases are released during decomposition.

Disposal considerations

Waste treatment methods

If wastes and/or containers cannot be disposed of according to the product label directions, disposal of this material must be in accordance with your local or area regulatory authorities. This information presented below only applies to the material as supplied. The identification based on characteristic(s) or listing may not apply if the material has been used or otherwise contaminated. It is the responsibility of the waste generator to determine the toxicity and physical properties of the material generated to determine the proper waste identification and disposal methods in compliance with applicable regulations. If the material as supplied becomes a waste, follow all applicable regional, national and local laws.