Registration Dossier
Registration Dossier
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EC number: 206-736-0 | CAS number: 371-41-5
Biodegradation in water and sediment: simulation tests
Administrative data
- Endpoint:
- biodegradation in water and sediment: simulation tests
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Prediction model
- Title:
- Biodegradation in water and sediment by Environmental Science Center’s PBT profiler
- Author:
- Environmental Science Center
- Year:
- 2 010
- Bibliographic source:
- PBT profiler, Office of Chemical Safety and Pollution Prevention , U.S. Environmental Protection Agency; version 1.301
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- PBT profiler database
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-fluorophenol
- EC Number:
- 206-736-0
- EC Name:
- 4-fluorophenol
- Cas Number:
- 371-41-5
- Molecular formula:
- C6H5FO
- IUPAC Name:
- 4-fluorophenol
- Test material form:
- solid: crystalline
- Details on test material:
- -Name of test material : 4-fluorophenol
- Molecular formula : C6H5FO
- Substance type: Organic
- Physical state: Solid
Constituent 1
- Radiolabelling:
- not specified
Study design
- Oxygen conditions:
- other: estimated database
Results and discussion
Mean total recoveryopen allclose all
- Compartment:
- other: water, material (mass) balance
- % Recovery:
- 19
- Compartment:
- other: sediment, material (mass) balance
- % Recovery:
- 0
% Degradationopen allclose all
- % Degr.:
- 50
- Parameter:
- test mat. analysis
- Sampling time:
- 38
- % Degr.:
- 50
- Parameter:
- test mat. analysis
- Sampling time:
- 340
Half-life of parent compound / 50% disappearance time (DT50)open allclose all
- Compartment:
- water
- DT50:
- 38 d
- Type:
- other: estimated
- Compartment:
- sediment
- DT50:
- 340 d
- Type:
- other: estimated
- Transformation products:
- not specified
Any other information on results incl. tables
Media |
Half life (days) |
Percent in Medium |
Water |
38 |
19% |
sediment |
340 |
0% |
Applicant's summary and conclusion
- Conclusions:
- Half life period of 4-fluorophenol in water was observed to be 38 days while in sediment it is 340 days.Based on these half life values of it is concluded that 4-fluorophenol is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is no diffusion of the substance in the sediment as evident from the reported data (0% in sediment) and hence persistence in the sediment compartment is not likely to be critical.
- Executive summary:
Based on level III fugacity model the half life period of 4-fluorophenol was estimated
Half life period of 4-fluorophenol in water was observed to be 38 days while in sediment it is 340 days.Based on these half life values of it is concluded that 4-fluorophenol is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is no diffusion of the substance in the sediment as evident from the reported data (0% in sediment) and hence persistence in the sediment compartment is not likely to be critical.
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