Registration Dossier
Registration Dossier
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EC number: 249-047-0 | CAS number: 28473-19-0
Endpoint summary
Administrative data
Description of key information
Additional information
DIDS was readily biodegradable in a GLP study, performed in accordance with OECD Guideline 301D (closed bottle test).
Additionally, the OECD QSAR Toolbox predicted total biodegradation and total removal of DIDS in a sewage treatment plant to be 0.78% and 94%, respectively, using EPI Suite (STP FM) (OECD, 2012).
DIDA, a structurally-related read-across compound, was readily biodegradable in a 28-day read biodegradability test in activated sludge, with 50.17 mg/L degraded by 76.46% (Anon, undated a). Another unpublished guideline study saw 72% biodegradation of DIDA in 28 days (Anon, undated b).
The ready biodegradability of DIDA and DIDS supports the use of DIDA for read-across purposes.
References
ACC (2010).American Chemistry Council.Robust summaries for aliphatic esters – diesters HPV Test Plan. 201-16837B.
http://www.epa.gov/hpv/pubs/summaries/alipestr/c13466rr8.pdf
Anon (undated a). Unpublished confidential data (cited in ACC, 2010).
Anon (undated b). P Confidential report #21 (cited in CCR).
CCR. Ecological Categorization Results from the Canadian Domestic Substances List. Record onHexanedioic acid, diisodecyl ester. Last accessed 5 April 2013.
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