Registration Dossier
Registration Dossier
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EC number: 209-842-5 | CAS number: 594-44-5
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- not specified
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data from Handbook or collection of data with no details
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- No information
- Author:
- Bingham, E.; Cohrssen, B.; Powell, C.H.
- Year:
- 2 001
- Bibliographic source:
- Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 7:747
Materials and methods
Test material
- Reference substance name:
- Ethanesulphonyl chloride
- EC Number:
- 209-842-5
- EC Name:
- Ethanesulphonyl chloride
- Cas Number:
- 594-44-5
- Molecular formula:
- C2H5ClO2S
- IUPAC Name:
- ethanesulfonyl chloride
Constituent 1
Test animals
- Species:
- rabbit
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- 200 - 2 000 mg/kg bw
- Mortality:
- A single dermal application of 2000 mg/kg to rabbits killed two of three animals. No deaths occurred following a dermal application of 200 mg/kg to rabbits.
Applicant's summary and conclusion
- Interpretation of results:
- Toxicity Category IV
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The dermal LD50 of the substance is between 200 and 2000 mg/kg bw in the rabbit. The substance is classified into the toxicity category IV.
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