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EC number: -
CAS number: -
The substance was negative in the following
1) Ames Test – salmonella &
2) In Vivo Mammalian Erythrocyte Micronucleus Test
No effects were noted in any of the studies
conducted. A repeat dose study with oral treatment in rats did not
reveal any tumorigenic properties which could be related to the
administration of the test substance. Consequently, the substance is
considered not to be potentially mutagenic.
for classification or non classification
studies have all been ranked reliability 1 according to the Klimisch et
al system. This ranking was deemed appropriate because the studies were
conducted to GLP and in compliance with agreed protocols. Sufficient
dose ranges and numbers are detailed; hence it is appropriate for use
based on reliability and animal welfare grounds.
results triggered no classification under the Dangerous Substance
Directive (67/548/EEC) and the CLP Regulation (EC No 1272/2008). No
classification for genetic toxicity is therefore required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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