Registration Dossier
Registration Dossier
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EC number: 231-198-9 | CAS number: 7446-14-2
Toxicity to other above-ground organisms
Administrative data
- Endpoint:
- toxicity to other above-ground organisms
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well-documented publication which meets basic scientific principles
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 988
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Soft tissue concentrations of lead, calcium, and magnesium were measured in the garden snail, Helix aspersa, over a 64-day dosing regime.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Lead sulphate
- EC Number:
- 231-198-9
- EC Name:
- Lead sulphate
- Cas Number:
- 7446-14-2
- Molecular formula:
- H2O4S.Pb
Constituent 1
Test organisms
- Test organisms (species):
- other: snail
Study design
- Study type:
- semi-field study
- Limit test:
- yes
- Total exposure duration:
- 64 d
Results and discussion
Any other information on results incl. tables
Levels of Ca in the snails from the two sites differ markedly.
Both groups showed a decline in Ca following the initial two days on the high Pb diet, though this reduction is only significant in the CP snails.
The high levels of Pb achieved in both groups without any increase of mortality indicate that the toxic metal is isolated in an innocuous form, as granules, or deposited in the shell.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In this study, lead sulphate was not found toxic for snail. However, Pb induced a change in Calcium metabolism.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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