Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 939-715-6 | CAS number: 1474044-78-4
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original report not available and documentation insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 977
- Report date:
- 1977
Materials and methods
- Study type:
- study with volunteers
- Endpoint addressed:
- skin irritation / corrosion
- Principles of method if other than guideline:
- In a Burckhardt test, a 5% solution of a soap formulation containing 0.2% of the test substance was applied 60 times within 30 minutes to the skin of 5 volunteers. The skin irritation effects were assessed during the exposure period.
- GLP compliance:
- no
Test material
- Reference substance name:
- 95912-87-1 (5% dilution of a 0.2% formulation)
- IUPAC Name:
- 95912-87-1 (5% dilution of a 0.2% formulation)
- Details on test material:
- - Name of test material (as cited in study report): only trade name given
- Analytical purity: no data
Constituent 1
Method
- Type of population:
- general
- Subjects:
- - Number of subjects exposed: 5
- Ethical approval:
- not specified
- Route of exposure:
- dermal
- Reason of exposure:
- intentional
- Exposure assessment:
- not specified
- Details on exposure:
- A 0.01% solution of the test substance (5% solution of a soap formulation containing 0.2% of the test substance ) was applied 60 times within 30 minutes to the skin of 5 volunteers. The skin irritation effects were assessed during the exposure period.
- Examinations:
- - Other: skin irritation
Results and discussion
- Results of examinations:
- - Other: 1/5 volunteers reported a mild burning feeling at the application site of one test substance batch from 20 minutes after exposure started, and blotchy redness was observed until 1 hour after exposure ended. The remaining 4 subjects did not show any effects.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
