Registration Dossier
Registration Dossier
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EC number: 202-770-5 | CAS number: 99-59-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The lethal concentration (LC50) value of 5-nitro-o-anisidine in fish (Pimephales promelas) in a 96 h study on mortality effect was estimated to be 207.4058mg/L. But the BCF value of 5-nitro-o-anisidine reported was not >= 500 as well as the substance was found to be rapidly degradable.Thus considering only the value from CLP Criteria for aquatic classification of the substance , it is concluded that 5-nitro-o-anisidine could not exhibit short term toxicity to fish (Pimephales promelas)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 207.406 mg/L
Additional information
The lethal concentration (LC50) value of 5-nitro-o-anisidine in fish (Pimephales promelas) in a 96 h study on mortality effect was estimated to be 207.4058mg/L. The supporting studies also predicted an LC50 value above 207.4 mg/L.
The various weight of evidence studies can be summarised as follows :
Sr. No |
Endpoint Name |
Value |
Unit | Species | Basis of effect |
| 1 | LC50 | 207.4058 | mg/L | Pimephales promelas | mortality |
| 2 | EC50 | 139.0646 | mg/L | Lepomis macrochirus | mortality |
| 3 | LC50 | 119.1158 | mg/L | Oncorhynchus mykiss | mortality |
But the BCF value of 5-nitro-o-anisidine reported was not >= 500 as well as the substance was found to be rapidly degradable.Thus considering only the value from CLP Criteria for aquatic classification of the substance , it is concluded that 5-nitro-o-anisidine could not exhibit short term toxicity to fish (Pimephales promelas)
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