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EC number: 215-656-5 | CAS number: 1337-83-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
By QSAR Toolbox version 3.3 predicted model the short term toxicity (LC50) in Oncorhynchus mykiss fish was estimated to be 6.446434498 mg/l for 96 hrs in static condition for test substance Undecenal with mortality effects.
But the test substance is readily biodegradable in water medium and also bioaccumulation concentration not≥500 (i.e 9.071 L/kg wet-wt) thus not fulfil the classification criteria of CLP and therefore the target chemical Undecenal (Cas no.1337-83-3)not consider for the aquatic classification.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 6.446 mg/L
Additional information
Various studies for the target chemical Undecenal (Cas no.1337-83-3) along with read across substance data were reviewed to summarize the following information:
96 hrs aquatic toxicity study conducted from predicted models SSS QSAR prediction model, 2016 and Danish QSAR using Battery, Leadscope and SciQSAR models (in domain) which estimates toxic effects of the test compound Undecenal (CAS no 1337-83-3). These estimated studies indicate that the short term toxicity (LC50) in Oncorhynchus mykiss fish was 6.446434498 mg/l in static condition and 1.426757 mg/l for 96 hrs with mortality effects respectively.
Another read across study for Undec-10-enal (Cas no. 112-45-8) from experimental result indicate that according to the OECD guideline 203 on Zebra fish (Danio rerio) in a fresh water static system at a nominal concentration level of 0.8 mg/L, 1.76 mg/L, 3.87 mg/L, 8.51 mg/L for 96 hrs.Observations for mortality, visible symptoms, pH, Temperature, dissolved oxygen content were recorded after 24 hours, 48 hours, 72 hours and 96 hours after the start of the experiment. No mortality was recorded in any of the concentration and the fishes were freely swimming without showing any abnormal symptoms. No mortalities were found in the control aquaria. Based on nominal concentrations used, experimental median no effect lethal concentration [LC-0 (96 h)] for the Undec-10-enal onDanio reriowas found to be 8.51 mg/L.
But the test substance is readily biodegradable in water medium and also bioaccumulation concentration not≥500 (i.e 9.071 L/kg wet-wt) thus not fulfil the classification criteria of CLP and therefore the target chemical Undecenal (Cas no.1337-83-3)not consider for the aquatic classification.
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