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Current Testing Proposals

Current Testing Proposals

Here you can find the substances and hazard endpoints for which ECHA is currently inviting third parties to submit scientifically valid information and studies.

Please also note the following:

 

The link under 'View dossier'

The link under 'View dossier' to the registered substances website allows easy access to the aggregated dossiers containing further details of the testing proposed including the test method (e.g. if an extended one-generation reproduction toxicity study has been proposed instead of a two-generation study). Related information on the substance subject to the testing proposal can also be seen through this link to the aggregated data per joint registration for a substance, which has been obtained from all registration dossiers that are part of that joint registration. If the related dossier has not yet been disseminated or the substance identity is confidential, such a link cannot be given.

The Total Tonnage Band published does not necessarily reflect the registered tonnage band(s) and associated information requirement obligations. For the 'Total Tonnage Band' of the disseminated dossier, compiled data is calculated from the non-confidential quantities of a substance manufactured and/or imported by all registrants, excluding any quantity directly used as an intermediate to produce a different chemical.  

 

Specific grounds for the testing proposal

In some cases, the registrant may propose testing under Annex IX and X of the REACH Regulation even if the registration tonnage band is lower than the tonnage band of the REACH Annex for which the test is proposed. Such specific testing proposals may be triggered by a concern identified from previous study results and their assessment in the chemical safety report (e.g. based on Annex I.0.5 or the second column of Annex VIII section 8.7.1). This is indicated with a note after each relevant endpoint showing that the testing proposal is based on a concern identified by the registrant.  

 

Read-across/category approach proposed

The registrant may have proposed to apply a read-across/category approach for one or more of the testing proposals based on adaptation according to Annex XI.1.5 of the REACH Regulation. This is indicated for the relevant testing proposal endpoint(s) with a note that testing is proposed for another substance than the registered substance, giving the proposed test substance name and, where available, the EC or CAS number.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below or the Previous Testing Proposals table. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 30 results.
Name EC Number CAS Number Deadline for submitting information Hazard endpoint for which vertebrate testing was proposed Link to the format for submitting information View dossier  
(3-chloropropyl)diethoxymethylsilane 236-828-6 13501-76-3 04/06/2015 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with (3-chloropropyl)triethoxysilane (CAS 5089-70-3) Give Comments
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 04/06/2015 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with (3-chloropropyl)triethoxysilane (EC 225-805-6)” Give Comments
(3E)-2-chloro-3-(hydroxymethylene)cyclohexene-1-carbaldehyde 801-656-8 1416808-92-8 04/06/2015 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. Give Comments
1,1'-(p-tolylimino)dipropan-2-ol 254-075-1 38668-48-3 04/06/2015 Sub-chronic toxicity (90-day): oral Give Comments
2,2-dimethyl-1,3-dioxolan-4-ylmethanol 202-888-7 100-79-8
04/06/2015
04/06/2015
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
2,2-dimethylpropan-1-ol, tribromo derivative 253-057-0 36483-57-5 04/06/2015 Reproductive toxicity (pre-natal developmental toxicity) Give Comments
2-benzofuran-1,3-dione; 2-(2-hydroxyethoxy)ethanol 608-744-3 32472-85-8 30/04/2015 Reproductive toxicity (pre-natal developmental toxicity) Give Comments
2-ethyl-2-[[(1-oxononyl)oxy]methyl]propane-1,3-diyl dinonan-1-oate 204-793-6 126-57-8 04/06/2015 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates Give Comments Link will be available soon.
2-methylbut-3-yn-2-ol 204-070-5 115-19-5 08/06/2015 Sub-chronic toxicity (90-day): oral Give Comments
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane 941-793-1 - 04/06/2015 Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2-Propyn-1-ol, compd. with methyloxirane (EC 609-530-2, CAS 38172-91-7) Give Comments
3,5-bis(2,4-dimethylcyclohex-3-en-1-yl)polyheterocycle - - 30/04/2015 Genetic toxicity in vivo Give Comments Note: Link to registration dossier not given as the substance identity is confidential.
[3-(triethoxysilyl)propyl]urea 245-876-7 23779-32-0
04/06/2015
04/06/2015
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
barium titanium trioxide 234-975-0 12047-27-7
04/06/2015
04/06/2015
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
cerium trinitrate 233-297-2 10108-73-3 04/06/2015 Reproductive toxicity (pre-natal developmental toxicity) Give Comments
dichlorocyclohexylmethylsilane 226-956-0 5578-42-7 30/04/2015 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [dicyclopentyldimethoxysilane] (CAS 126990-35-0) Give Comments
dipotassium heptafluorotantalate 240-986-1 16924-00-8 30/04/2015 Genetic toxicity in vivo Give Comments
Fatty acids, C16-18, reaction products with diethanolamine 293-014-3 91032-08-5 30/04/2015 Reproductive toxicity (pre-natal developmental toxicity) Give Comments
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and tetraethylenepentamine 500-289-8 103758-98-1
30/04/2015
30/04/2015
Reproductive toxicity (pre-natal developmental toxicity) ||Note: testing proposed with [Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine] (CAS 68082-29-1)
Sub-chronic toxicity (90-day): oral ||Note: testing proposed with [Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine] (CAS 68082-29-1)
methylsilanetriyl triacetate 224-221-9 4253-34-3 30/04/2015 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [Trimethoxy(methyl)silane] (EC 214-685-0) Give Comments
N-octadecylstearamide 236-276-6 13276-08-9
04/06/2015
04/06/2015
04/06/2015
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
Phosphoric acid, butyl ester 235-826-2 12788-93-1
04/06/2015
04/06/2015
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
Phosphoric acid, octadecyl ester 254-466-7 39471-52-8
04/06/2015
04/06/2015
04/06/2015
04/06/2015
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
Reaction mass of [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid and Phosphonic acid, P-[(tetrahydro-2-hydroxy-2-oxido-4H-1,4,2-oxazaphosphorin-4-yl)methyl]- 911-811-2 -
04/06/2015
04/06/2015
04/06/2015
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
Reaction mass of potassium ethyl octylphosphonate and diethyl octylphosphonate 939-595-5 - 04/06/2015 Reproductive toxicity (pre-natal developmental toxicity) Give Comments
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-C13 odd-numbered alkyl) derivs. and sodium hydroxide and chloroacetic acid 938-645-3 -
30/04/2015
30/04/2015
30/04/2015
Long-term toxicity to fish Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11 alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 271-794-6)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
Sub-chronic toxicity (90-day): oral Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
sodium p-cumenesulphonate 239-854-6 15763-76-5 12/06/2015 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate Give Comments
tellurium dioxide 231-193-1 7446-07-3 30/04/2015 Sub-chronic toxicity (90-day): oral Give Comments
tert-butyl α,α-dimethylbenzyl peroxide 222-389-8 3457-61-2 30/04/2015 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates Give Comments
Triethoxyoctylsilane 220-941-2 2943-75-1 04/06/2015 Long-term toxicity to fish || Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1) Give Comments
tripotassium propylsilanetriolate 299-135-8 93857-00-2
30/04/2015
30/04/2015
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7)
Sub-chronic toxicity (90 day): inhalation Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7)
Showing 30 results.


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