Substance Information

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REACH Registration data can be found in the new ECHA CHEM database. The old ‘Registered substance factsheets’ will be available on this web site during the transition period but have not been updated since 19 May 2023. More

 

Substance Infocard

IC

2,2',2''-nitrilotriethanol

Help Substance identity

The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas.

Some substance identifiers may have been claimed confidential, or may not have been provided, and therefore not be displayed.

EC (European Community) Number

The EC Number is the numerical identifier for substances in the EC Inventory. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). More information about the EC Inventory can be found here.

If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9.

The EC or list number is the primary substance identifier used by ECHA.

CAS (Chemical Abstract Service) registry number

The CAS number is the substance numerical identifier assigned by the Chemical Abstracts Service, a division of the American Chemical Society, to substances registered in the CAS registry database. A substance identified primarily by an EC or list number may be linked with more than one CAS number, or with CAS numbers that have been deleted. More information about CAS and the CAS registry can be found here.

Molecular formula

The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. This information is only displayed if the substance is well–defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure.

Molecular structure

The molecular structure is based on structures generated from information available in ECHA’s databases. If generated, an InChI string will also be generated and made available for searching. This information is only displayed if the substance is well-defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure.

More help available here.

EC / List no.: 203-049-8

CAS no.: 102-71-6

Mol. formula: C6H15NO3

formula
Help Hazard classification and labelling

The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH).

This section is based on three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). The source of the information is mentioned in the introductory sentence of the hazard statements. When information is available in all sources, the first two are displayed as a priority.

Please note:

The purpose of the information provided under this section is to highlight the substance hazardousness in a readable format. It does not represent a new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects described, such as duration of exposure or substance concentration (e.g. in case of consumer and professional uses). Other relevant information includes the following:

  • Substances may have impurities and additives that lead to different classifications. If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. However, substance notifications in the InfoCard are aggregated independently of the impurities and additives.
  • Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or the UN Global Harmonised System (GHS).

To see the full list of notified classifications and to get more information on impurities and additives relevant to classification please consult the C&L Inventory.

More information about Classification and Labelling is available in the Regulations section of ECHA website.

More help available here.

Harmonised classification and labelling (CLH)

Harmonised classification and labelling is a legally binding classification and labelling for a substance, agreed at European Community level. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment.

The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information.

If the substance is covered by more than one CLH entry (e.g. disodium tetraborate EC no. 215–540–4, is covered by three harmonisations: 005–011–00–4; 005–011–01–1 and 005–011–02–9), CLH information cannot be displayed in the InfoCard as the difference between the CLH classifications requires manual interpretation or verification. If a substance is classified under multiple CLH entries, a link to the C&L Inventory is provided to allow users to view CLH information associated with the substance and no text is automatically generated for the InfoCard.

It is possible that a harmonisation is introduced through an amendment to the CLP Regulation. In that case, the ATP (Adaptation to Technical Progress) number is displayed.

More info on CLH can be found here.

Classification and labelling under REACH

If available, additional information on classification and labelling (C&L) is derived from REACH registration dossiers submitted by industry. This information has not been reviewed or verified by ECHA, and may change without prior notice. REACH registration dossiers have greater data requirements (such as supporting studies) than do notifications under CLP.

Notifications under the Classification Labelling and Packaging (CLP) Regulation

If no EU harmonised classification and labelling exists and the substance was not registered under REACH, information derived from classification and labelling (C&L) notifications to ECHA under CLP Regulation is displayed under this section. These notifications can be provided by manufacturers, importers and downstream users. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information.

Note that for readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed.

Danger! According to the classification provided by companies to ECHA in REACH registrations this substance causes serious eye damage and is suspected of damaging fertility or the unborn child.

Helpful information About this substance

This section provides an overview of the calculated volume at which the substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here.

The use information is displayed per substance life cycle stage (consumer use, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites or in manufacturing). The information is aggregated from the data coming from REACH substance registrations provided by industry.

For a detailed overview on identified uses and environmental releases, please consult the registered substance factsheet.

Use descriptors are adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes described in Chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment.

The examples provided are generic examples and may not apply to the specific substance you are viewing. A substance may have its use restricted to certain articles or products and therefore not all the examples may apply to the specific substance. Furthermore, some substances can be found in an article, but with unlikely exposure (e.g. inside a watch) or with very low concentrations considered not to pose risks to human health or the environment.

Please note:

For readability purpose, only non-confidential use descriptors occurring in more than 5% of total occurrences are displayed.

The described Product category (i.e. the products in which the substance may be used) may refer to uses as intermediate and under controlled conditions, for which there is no consumer exposure.

More help is available here.

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses

This substance is used in the following products: cosmetics and personal care products, washing & cleaning products, polishes and waxes, polymers, air care products, pH regulators and water treatment products, lubricants and greases, perfumes and fragrances, coating products and inks and toners.
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Article service life

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).
Other release to the environment of this substance is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).
This substance can be found in complex articles, with no release intended: vehicles.
This substance can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), leather (e.g. gloves, shoes, purses, furniture), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).

Widespread uses by professional workers

This substance is used in the following products: washing & cleaning products, lubricants and greases, metal working fluids, laboratory chemicals, textile treatment products and dyes and coating products.
This substance is used in the following areas: printing and recorded media reproduction, building & construction work, municipal supply (e.g. electricity, steam, gas, water) and sewage treatment and scientific research and development.
This substance is used for the manufacture of: textile, leather or fur, plastic products and machinery and vehicles.
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Formulation or re-packing

This substance is used in the following products: coating products, cosmetics and personal care products, metal surface treatment products, inks and toners, pH regulators and water treatment products, lubricants and greases, paper chemicals and dyes, plant protection products, leather treatment products and textile treatment products and dyes.
Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

Uses at industrial sites

This substance is used in the following products: paper chemicals and dyes, textile treatment products and dyes, inks and toners, leather treatment products, polymers, pH regulators and water treatment products, laboratory chemicals, lubricants and greases and metal working fluids.
This substance is used in the following areas: scientific research and development and formulation of mixtures and/or re-packaging.
This substance is used for the manufacture of: chemicals, pulp, paper and paper products and textile, leather or fur.
Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, in the production of articles, of substances in closed systems with minimal release and as an intermediate step in further manufacturing of another substance (use of intermediates).

Manufacture

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Help Important to know

This section highlights four regulatory activities or outcomes under REACH – Registration, Evaluation, Authorisation and Restriction of Chemicals – Regulation (EC) No 1907/2006:

  • Community rolling action plan - indicates if the substance is or was included in the Community rolling action plan (CoRAP). The CoRAP list includes substances that could pose a risk to human health or the environment and whose (potentially hazardous) properties are to be evaluated by the Member States in the next three years. After evaluation, proposals may be made for further regulatory action regarding the substance.
  • Candidate List - indicates if the substance is included in the candidate list of substances of very high concern (SVHCs). The Candidate List includes substances that are subject to additional protocols and reporting obligations and which may eventually be included in the Authorisation List, further limiting their use.
  • Authorisation list (Annex XIV to REACH) - indicates if the substance is included in the Authorisation list. These substances cannot be placed on the market or used after a given date, unless an authorisation is granted for their specific use, or the use is exempted from authorisation.
  • Restriction list (Annex XVII to REACH) - indicates if the substance is included in the Restriction List. The Restriction List describes the conditions for the manufacture, placing on the market or use of certain substances, either on their own or in mixtures or articles.

Please note: The identification of relevant regulatory activities and outcomes is done automatically and without manual verification. Substances may be grouped together under a specific regulatory activity for more efficient risk management and legislative processing (e.g. restriction on "Lead and its compounds"). In these cases, Infocards may not identify all substances in the group.Therefore it does not represent official and legally–binding information. To confirm if a substance is covered by a specific regulatory action the official publication, e.g. the electronic edition of the Official Journal of the European Union should be consulted.

More help available here.

Help How to use it safely

This section provides links to the list of precautions (precautionary statements) and to the guidance on safe use, if they have been provided in REACH registration dossiers.

  • Precautionary statements - describe recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product or improper storage or handling of a hazardous product.
  • Guidance on safe use - recommendations by substance registrant on the proper use of the substance in various situations. Examples include recommended measures on fire-fighting, transport and recycling and disposal.

Please note: Precautionary measures and guidance on safe use concern the use and handling of the specific substance as such, not of the presence of the substance in other articles or mixtures. The precautionary measures and guidance on safe use are as submitted to ECHA by registrants under the REACH Regulation. Information on precautionary measures and the safe use is submitted by the registrant of a substance and the registrant is solely responsible for its accuracy and completeness.

More help available here.

about INFOCARD - Last updated: 16/09/2023 InfoCard

The InfoCard summarises the non-confidential data of a substance held in the databases of the European Chemicals Agency (ECHA). InfoCards are generated automatically based on the data available at the time of generation.

The quality and correctness of the information submitted to ECHA remains the responsibility of the data submitter. The type of uses and classifications may vary between different submissions to ECHA and for a full understanding it is recommended to consult the source data. Information on applicable regulatory frameworks is also automatically generated and may not be complete or up to date. It is the responsibility of the substance manufacturers and importers to consult official publications, e.g. the electronic edition of the Official Journal of the European Union.

InfoCards are updated when new information is available. The date of the last update corresponds to the publication date of the InfoCard and not necessarily to the date in which the update occurred in the source data.

More help available here.

Help Help

Key datasets

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Regulatory context

Here you can find all of the regulations and regulatory lists in which this substance appears, according to the data available to ECHA. This substance has been found in the following regulatory activities (directly, or inheriting the regulatory context of a parent substance):

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation
CLP - Classification, Labelling and Packaging
  • Substances for which classification and labeling data have been submitted to ECHA in a registration under REACH or notified by manufacturers or importers under CLP. Such notifications are required for hazardous substances, as such or in mixtures, as well as for all substances subject to registration, regardless of their hazard.
Previous Legislations
  • Substances listed in the EINECS, ELINCS, or NLP inventories.
Food Contact Recycled Plastic Materials and Articles Regulation-repealed
  • FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use
    EU. Plastic Food Contact Materials (FCMs) per Regulation 10/2011/EU (Union List), Directive 282/2008/EC on Recycled Plastic FCMs, 28 March 2008, amended by Regulation 2015/1906/EU, 23 October 2015

    This list contains the Annex I Plastic Food Contact Materials (FCMs) authorised for use in the European Union under Regulation 10/2011/EU. Pursuant to Art. 4(b) of Directive 282/2008/EC on recycled plastic FCMs, plastic recycling processes can only be authorised if input originates from plastic materials and articles manufactured in accordance with EU legislation on plastic food contact materials and articles.

Plastic Materials and Articles Regulation
  • FCM and Articles Regulation, Annex I - Authorised Substances
    EU. Union List of Authorized Substances: Annex I, Plastics Food Contact Regulation 10/2011/EU, as amended by Regulation (EU) 2023/1627, OJ L 201, 11 August 2023

    This list contains the Union list of authorised monomers, other starting substances, macromolecules obtained from microbial fermentation, additives and polymer production aids. It is taken from Annex I of the Commission Regulation (EU) No 10/2011 on plastic materials and articles intended to come into contact with food.

Recycled Plastic Food Contact Materials
  • Recycled Plastic FCMs - Regulation (EU) 2022/1616
    EU. Recycled Plastic FCMs per Regulation 10/2011/EU (Union List), Regulation (EU) 2022/1616, OJ L 243 of 20 September 2022, as corrected by a corrigendum, OJ L 244 of 21 September 2022

    The list contains the Union list of authorised substances for the purposes of compositional requirements related to recycled plastic FCMs. The list is taken from Annex I to Commission Regulation (EU) No 10/2011. Recycled plastic FCMs shall comply with the requirements set out in Regulation (EU) No 10/2011. In addition, plastic waste inputs shall originate only from plastic materials and articles manufactured in accordance with Regulation (EU) No 10/2011.

Help Help

Substance names and other identifiers

Regulatory process names
2,2',2''-nitrilotriethanol
EC Inventory, Pre-Registration process
2,2',2''-nitrilotriethanol
Substance Evaluation - CoRAP, Pre-Registration process
triethanolamine
FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Recycled Plastic FCMs - Regulation (EU) 2022/1616
Trolamine
Other
IUPAC names
,2',2''-nitrilotriethanol
C&L Inventory
2,2',2" -nitrilotriethanol
C&L Inventory, Registration dossier
2,2',2"-Nitrilotrietanol
C&L Inventory
2,2',2"-Nitrilotriethanol
C&L Inventory
2,2',2"-nitrilotriethanol
C&L Inventory
2,2',2"-nitrilotrisethanol
C&L Inventory
2,2',2"-Nitrolotriethanol
C&L Inventory
2,2',2''-nitriloethanol
C&L Inventory
2,2',2''-Nitrilotri(ethan-1-ol)
Registration dossier
2,2',2''-NITRILOTRIETANOLO
C&L Inventory
2,2',2''-nitrilotriethano
C&L Inventory
2,2',2''-Nitrilotriethanol
C&L Inventory, Registration dossier
2,2',2''-nitrilotriethanol
C&L Inventory, Registration dossier
2,2',2''-Nitrilotriethanol
Registration dossier
2,2',2''-nitrilotriethanol
Registration dossier
2,2',2''-nitrilotriethanol - OR30
Registration dossier
2,2',2II-nitrilotriethanol
C&L Inventory
2,2,2-nitrilotriethanol
C&L Inventory
2,2`,2``-nitrilotriethanol
C&L Inventory
2,2´,2´´-nitrilotriethanol
C&L Inventory
2-(bis(2-hydroxyethyl)amino)ethanol
C&L Inventory, Registration dossier
2-[Bis (2-hydroxyethyl) amino]ethanol
C&L Inventory
2-[bis(2-hydroxyethyl)amino]ethan-1-ol
C&L Inventory, Registration dossier, Other
2-[bis(2-hydroxyethyl)amino]ethanol
C&L Inventory, Registration dossier, Other
2-[bis(2-hydroxyethyl)amino]ethanol.
C&L Inventory
Agent I805
Registration dossier
Ethanol, 2,2',2"-nitrilotris-
C&L Inventory
Ethanol, 2,2',2''-nitrilotris-
C&L Inventory
TAE, Triethanolamine
Registration dossier
TEA
Registration dossier
TEA, triethanolamine
Registration dossier
Treiethannolamine
C&L Inventory
Triethanolamin
C&L Inventory
triethanolamin
C&L Inventory
TRIETHANOLAMINE
C&L Inventory
Triethanolamine
C&L Inventory
triethanolamine
C&L Inventory
TRIETHANOLAMINE
C&L Inventory
Triethanolamine
Registration dossier
triethanolamine
Registration dossier
Triethanolanmin
C&L Inventory
Triethyanolamine
Registration dossier
Tris(2-hydroxyethyl)amine
C&L Inventory, Registration dossier
trithanolamine
C&L Inventory
Trade names
2,2',2''-Nitrilotriethanol
Registration dossier
2,2',2''-Nitrilotris[ethanol]
Registration dossier
Agent I805
Registration dossier
Alkanolamine 244
Registration dossier
CIM-68
Registration dossier
Daltogen
Registration dossier
Ethanol, 2,2',2''-nitrilotri- (8CI)
Registration dossier
Ethanol, 2,2',2''-nitrilotris- (9CI)
Registration dossier
Neonor 20
C&L Inventory
Nitrilotriethanol
Registration dossier
Sterolamide
Registration dossier
Sting-Kill
Registration dossier
TEA
Registration dossier
TEA (amino alcohol)
Registration dossier
TEOA
Registration dossier
Thiofaco T 35
Registration dossier
Thiofaco T35
Registration dossier
Trietanolamina 85%
Registration dossier
Trietanolamina 99%
Registration dossier
Trietanolamina 99% D85
Registration dossier
Trietanolamina 99% D95
Registration dossier
Trietanolamina grado aditivo
Registration dossier
Triethanolamin
Registration dossier
TRIETHANOLAMINE
C&L Inventory, Registration dossier
Triethanolamine
Registration dossier
TRIETHANOLAMINE 80%
Registration dossier
TRIETHANOLAMINE COMMERCIAL LOW FREEZING GRADE (PM-4447)
Registration dossier
TRIETHANOLAMINE, 99%
Registration dossier
TRIETHANOLAMINE, Commercial Grade
Registration dossier
Tris(2-hydroxyethyl)amine
Registration dossier
Tris(β-hydroxyethyl)amine
Registration dossier
Trolamine
Registration dossier
Other names
TRIETHANOLAMINE
Pre-Registration process
Other identifiers
102-71-6
EC Inventory, C&L Inventory, Substance Evaluation - CoRAP, Registration dossier, Pre-Registration process, FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Recycled Plastic FCMs - Regulation (EU) 2022/1616, Other
CAS number
105655-27-4
Other
CAS number
126068-67-5
Other
CAS number
1429745-86-7
Other
CAS number
36549-53-8
Other
CAS number
36549-54-9
Other
CAS number
36549-55-0
Other
CAS number
36659-79-7
Other
CAS number
464917-26-8
Other
CAS number