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Short-term toxicity to aquatic invertebrates

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Description of key information

With high probability acutely not harmful to aquatic invertebrates.

Key value for chemical safety assessment

Additional information

The acute toxicity of 2 -morpholinoethanol (CAS 622 -40 -2) was assessed via a read-across approach since no experimental data are available for this substance. Test data for Daphnia magna were taken from studies with other N-substituted morpholine structures. All studies are reliable with restrictions since no chemical verification of the test item concentrations was performed.

The following data were used:

- 4 -Methylmorpholine (CAS 109 -02 -4): 48 -h EC50 > 100 mg/L (Directive 79/831/EEC, Annex V, Part C.2; BASF AG, 1991; Study No. 1/91/0270/50/1)

- 4 -Morpholinecarbaldehyde (CAS 4394 -85 -8): 48 -h EC50 > 500 mg/L (Directive 79/831/EEC, Annex V, Part C.2; BASF AG, 1987; Study No. 1/1679/2/88)

- 4 -Ethylmorpholine (CAS 100 -74 -3): 48 -h EC50 = 580 mg/L (DIN 38412, Part 11; BASF AG, 1989; Study No. 01/89/0733)

Taking these values, it can be concluded that 2 -morpholinoethanol is acutely not harmful to aquatic invertebrates with a high probability.