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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study with analytical test item concentration verification

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report Date:
1993

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): 2.6 -DCPTFMA
- Analytical purity: 89.7 %

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Daphnia magna
Details on test organisms:
laboratory cultures maintained in the Aquatic Ecotoxicology facilities, Rhane-Poulenc Agro Research Center - 06560 Sophia Antipolis, France

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h

Test conditions

Hardness:
ca. 180 mg/l CaCO3
Test temperature:
18 - 22 °C
pH:
7.8 - 8.2
Dissolved oxygen:
8.0 - 8.2 mg/l
Nominal and measured concentrations:
Nominal test concentrations (mg/L): 4.50, 2.50, 1.39, 0.77, 0.43, 0.24 and 0.13 mg/l.
Mean measured tested concentrations were 2.2, 1.5, 0.68, 0.38, 0.25, 0.14 and 0.08 mg/l
Details on test conditions:
TEST SYSTEM
- No. of vessels per concentration (replicates): 2
- No. of vessels per control (replicates): 2
- 10 daphnides per vessel
Reference substance (positive control):
yes
Remarks:
K2Cr2O7

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
1.59 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
mobility
Remarks on result:
other: 1.25 - 2.09 mg/l 95% CL

Applicant's summary and conclusion