Registration Dossier

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001
Report Date:
2002

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other:

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals / tissue source

Species:
other:

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
conjunctivae score
Basis:
animal #1
Time point:
other:
Score:
3
Max. score:
3
Reversibility:
fully reversible within:
Irritation parameter:
conjunctivae score
Basis:
animal #2
Time point:
other:
Score:
3
Max. score:
3
Reversibility:
fully reversible within:
Irritation parameter:
conjunctivae score
Basis:
animal #3
Time point:
other:
Score:
2.7
Max. score:
3
Reversibility:
fully reversible within:
Irritation parameter:
chemosis score
Basis:
animal #1
Time point:
other:
Score:
3
Max. score:
4
Reversibility:
fully reversible within:
Irritation parameter:
chemosis score
Basis:
animal #2
Time point:
other:
Score:
3
Max. score:
4
Reversibility:
not fully reversible within:
Remarks on result:
other:
Irritation parameter:
chemosis score
Basis:
animal #3
Time point:
other:
Score:
3
Max. score:
4
Reversibility:
fully reversible within:
Irritation parameter:
cornea opacity score
Basis:
animal #1
Time point:
other:
Score:
2
Max. score:
4
Reversibility:
fully reversible within:
Irritation parameter:
cornea opacity score
Basis:
animal #2
Time point:
other:
Score:
2
Max. score:
4
Reversibility:
not fully reversible within:
Remarks on result:
other:
Irritation parameter:
cornea opacity score
Basis:
animal #3
Time point:
other:
Score:
2
Max. score:
4
Reversibility:
fully reversible within:
Irritation parameter:
iris score
Basis:
animal #1
Time point:
other:
Score:
0.7
Max. score:
2
Reversibility:
fully reversible within:
Irritation parameter:
iris score
Basis:
animal #2
Time point:
other:
Score:
1
Max. score:
2
Reversibility:
fully reversible within:
Irritation parameter:
iris score
Basis:
animal #3
Time point:
other:
Score:
1
Max. score:
2
Reversibility:
fully reversible within:

Applicant's summary and conclusion