Registration Dossier
Registration Dossier
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EC number: 406-760-3 | CAS number: 42221-52-3 2,3,4,5-TETRACHLORBENZOYLCHLORID
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2,3,4,5-tetrachlorobenzoylchloride
- EC Number:
- 406-760-3
- EC Name:
- 2,3,4,5-tetrachlorobenzoylchloride
- Cas Number:
- 42221-52-3
- Molecular formula:
- C7HCl5O
- IUPAC Name:
- 2,3,4,5-tetrachlorobenzoyl chloride
Constituent 1
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
Study design
- Test type:
- static
- Water media type:
- not specified
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- The hardness of the dilution water used was 15.2 °dH 271 mg/L CaCO3).
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 2 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
Any other information on results incl. tables
- Sublethal observations / clinical signs:
All results are expressed in terms of nominal concentrations. GC-analysis showed no signal for the substance or metabolites. Therefore, DOC-analysis was chosen to give an indication of actual concentrations. The limit of water solubility under test conditions was below the LOD (5 mg/L) of the DOC determination.
Applicant's summary and conclusion
- Conclusions:
- Up to the water solubility of the test item (and its hydrolysis products) under exposure conditions no toxic effects were determined.
All results are expressed in terms of nominal concentrations. GC-analysis showed no signal for the substance or metabolites. Therefore, DOC-analysis was chosen to give an indication of actual concentrations. The Limit of water solubility under test conditions was below the LOD (5 mg/L) of the DOC determination.
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