Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 437-320-9 | CAS number: 16606-55-6 (R)-1,2-PROPYLENE CARBONATE
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Guidance on Safe Use
Administrative data
First-aid measures
Emergency measure - Inhalation: Remove casualty to fresh air and provide warmth and rest. If
necessary seek medical advice.
Emergency measure - Eyes: Immediately wash out eye thoroughly with plenty of water
until irritation subsides. If irritation persists, seek
medical advice.
Emergency measure - Skin: Immediately wash contaminated skin with soap and large
quantities of water. If necessary seek medical advice.
Emergency measure - Ingestion: Seek medical attention
Fire-fighting measures
Recommended extinguishing agent: Water spray, carbon dioxide, polyvalent powder, or foam.
Product arising from burning: Oxides of carbon
Product determined by test: N
Protective equipment: Full protective clothing and self-contained breathing
apparatus must be worn.
Accidental release measures
Emergency measures in case of spillage: Evacuate personnel from immediate vicinity.
Wear appropriate personal protective equipment conforming to
the relevant national or international standards as
mentioned in section 2.3.10.
Absorb spillages of solutions with a suitable inert material
(eg sand or soil). Carefully transfer the spillage to waste
containers, or use a sealed industrial vacuum machine.
Containers filled with waste material must be labelled in
the same way as the original containers.
Dispose of waste material by incineration in accordance with
local regulations.
Handling and storage
Handling: The substance should be stored handled and used in
conditions of good industrial hygiene and in conformity with
any local regulations in order to avoid exposure.
Engineering controls are necessary to reduce exposure to the
substance.
When exposure cannot be prevented or adequately controlled
appropriate personal protective equipment should be worn.
Such protective equipment should conform to the appropriate
international or national standards as follows:
Chemical protective gloves (eg to Standard EN374)
Chemical resistant clothing to (eg to Standard EN368)
Eye protection to (eg to Standard EN166)
When necessary appropriate respiratory protection should be
used such as a ventilated hood or cartridge mask.
Before any maintenance operations, the equipment should be
cleaned and decontaminated by qualified personnel. An
analysis of the risks should be performed and if an exposure
risk is identifed, the wearing of protective equipment is
recommended and specified.
Storage: Store in a dry, well ventilated area.
Keep container tightly closed.
Packaging of the substance and or preparation: Polylined steel drums.
Transport information
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Marine transport (UN RTDG/IMDG)
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Air transport (UN RTDG/ICAO/IATA)
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Special provisions / remarks
- Remarks:
- Transport: None.
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Exposure controls / personal protection
Stability and reactivity
Danger other than fire: None reported
Chemical reaction with water: None reported
Dust explosion: Not applicable
Dust explosion determined by test: N
Disposal considerations
Industry - Possibility of recovery/recycling: Discharge to the environment will be minimal. Recovery from
minor spillages or accidental discharge is not economically
or technically feasible, and such waste material will be
disposed of by incineration. In principle, it may be
possible to recover larger spillages of uncontaminated
material for subsequent use.
Industry - Possibility of neutralisation: The notification tests have revealed no hazardous effects.
Industry - Possibility of destruction: controlled discharge: Contaminated containers or spillages of solutions mixed with
inert material (eg sand or soil) should not be disposed of
by landfill.
Industry - Possibility of destruction - incineration: The substance can be disposed of by incineration by burning
under controlled conditions at a licensed waste treatment
processor in accordance with local regulations. Stack gases
should be scrubbed, because noxious fumes (eg carbon oxides)
could be formed.
Industry - Possibility of destruction - water purification: The substance should not normally be discharged directly to
the sewage system or aqueous environment.
Industry - Possibility of destruction - other: None.
Public at large - Possibility of recovery/recycling: Not applicable.
Public at large - Possibility of neutralisation: Not applicable.
Public at large - Possibility of destruction: controlled discharge: Not applicable.
Public at large - Possibility of destruction - incineration: Not applicable.
Public at large - Possibility of destruction - water purification: Not applicable.
Public at large - Possibility of destruction - others: Not applicable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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